Evidence map›Paper›PMID 31781850›Full record

ArticleInternational journal of legal medicine2020

Identification of human remains using Rapid DNA analysis.

Rosemary S Turingan, Jessi Brown, Ludmila Kaplun, Jake Smith, Jenna Watson, Derek A Boyd, Dawnie Wolfe Steadman, Richard F Selden

Open access · hybridAbstract read
In one paragraph

Article in International journal of legal medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 79 citations in OpenAlex.

  1. Pooled it
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  5. Review
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  8. Article
  9. Alternative workflows for identifying transnational missing persons.Forensic science international. Synergy · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Rosemary S TuringanANDE Corporation, 266 Second Avenue, Waltham, MA, 02451, USA.
Jessi BrownANDE Corporation, 266 Second Avenue, Waltham, MA, 02451, USA.
Ludmila KaplunANDE Corporation, 266 Second Avenue, Waltham, MA, 02451, USA.
Jake SmithDepartment of Anthropology, The University of Tennessee Knoxville, Knoxville, TN, 37996, USA.
Jenna WatsonDepartment of Anthropology, The University of Tennessee Knoxville, Knoxville, TN, 37996, USA.
Derek A BoydDepartment of Anthropology, The University of Tennessee Knoxville, Knoxville, TN, 37996, USA.
Dawnie Wolfe SteadmanDepartment of Anthropology, The University of Tennessee Knoxville, Knoxville, TN, 37996, USA.
Richard F SeldenANDE Corporation, 266 Second Avenue, Waltham, MA, 02451, USA. rfs4n6@ANDE.com.ORCID http://orcid.org/0000-0002-0741-0913
University of Tennessee at Knoxville · USMetal Matrix Cast Composites (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rapid identification of human remains following mass casualty events is essential to bring closure to family members and friends of the victims. Unfortunately, disaster victim identification, missing persons identification, and forensic casework analysis are often complicated by sample degradation due to exposure to harsh environmental conditions. Following a mass disaster, forensic laboratories may be overwhelmed by the number of dissociated portions that require identification and reassociation or compromised by the event itself. The interval between the disaster and receipt of victim samples at a laboratory is critical in that sample quality deteriorates as the postmortem interval increases. When bodies decompose due to delay in collection, transport, and sample processing, DNA becomes progressively fragmented, adversely impacting identification. We have previously developed a fully automated, field-forward Rapid DNA identification system that produces STR profiles (also referred to as DNA IDs or DNA fingerprints) from buccal and crime scene samples. The system performs all sample processing and data interpretation in less than 2 h. Here, we present results on Rapid DNA identification performed on several tissue types (including buccal, muscle, liver, brain, tooth, and bone) from exposed human bodies placed above ground or stored in a morgue/cooler, two scenarios commonly encountered following mass disasters. We demonstrate that for exposed remains, buccal swabs are the sample of choice for up to 11 days exposure and bone and tooth samples generated excellent DNA IDs for the 1-year duration of the study. For refrigerated remains, all sample types generated excellent DNA IDs for the 3-month testing period.

Indexed as

Postmortem ChangesBody RemainsBone and BonesDisaster VictimsDNADNA FingerprintingFemaleForensic AnthropologyForensic GeneticsHumansMaleMass Casualty IncidentsMusclesSpecimen HandlingTime FactorsToothDNADisaster victim identificationFlexPlexRapid DNA identificationShort tandem repeat

Identifiers

PMID31781850
PMCPMC7181457
OpenAlexW2990651013

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.