ArticleClinical neuroradiology2020
Collateral Scores in Acute Ischemic Stroke : A retrospective study assessing the suitability of collateral scores as standalone predictors of clinical outcome.
Article in Clinical neuroradiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed, 28 citations in OpenAlex.
- Tie2-Dependent Mechanisms Influence Leptomeningeal Collateral Dynamics and Reperfusion Following Stroke.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Article
- Multi-phase CT-Angiography outperforms angiographic careggi collateral score and predicts functional outcome in acute ischemic stroke.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025Article
- Evaluation of the relationship between computed tomography angiography collateral scores and clinical outcome.Arquivos de neuro-psiquiatria · 2024Article
- Inter-Rater Reliability of Collateral Status Assessment Based on CT Angiography: A Retrospective Study of Middle Cerebral Artery Ischaemic Stroke.Journal of clinical medicine · 2023Article
- Pivotal role of multiphase computed tomography angiography for collateral assessment in patients with acute ischemic stroke.La Radiologia medica · 2023Review
- Mechanical thrombectomy in stroke patients with acute occlusion of the M1- compared to the M2-segment: Safety, efficacy, and clinical outcome.The neuroradiology journal · 2022Article
- RAPID CT Perfusion-Based Relative CBF Identifies Good Collateral Status Better Than Hypoperfusion Intensity Ratio, CBV-Index, and Time-to-Maximum in Anterior Circulation Stroke.AJNR. American journal of neuroradiology · 2022Article
- Leptomeningeal anastomoses: Mechanisms of pial collateral remodeling in ischemic stroke.WIREs mechanisms of disease · 2022Review
- Cerebral Circulation Time After Thrombectomy: A Potential Predictor of Outcome After Recanalization in Acute Stroke.Journal of the American Heart Association · 2022Article
- Role of diabetes in collateral status assessed in CT perfusion-derived dynamic CTA in anterior circulation stroke.Neuroradiology · 2022Article
- Quantitative collateral score for the prediction of clinical outcomes in stroke patients: Better than visual grading.Frontiers in neuroscience · 2022Article
- Variability of acquisition phase of computed tomography angiography in acute ischemic stroke in a real-world scenario.European radiology · 2022Article
- Relationship between the degree of recanalization and functional outcome in acute ischemic stroke is mediated by penumbra salvage volume.Journal of neurology · 2021Article
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Authors and funding
8 authors at 2 institutions in 2 countries.
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No grant is acknowledged in the PubMed record.
Abstract
background and purposeSeveral collateral scores have been published for stroke in the middle cerebral artery territory, each considering different aspects of cerebral collateralization. Currently, there is no gold standard in CT-based collateral assessment. The aim of this retrospective study was to compare five collateral scores and determine whether they are able to predict clinical outcome after thrombectomy as standalone parameters.
methodsInclusion criteria were M1 occlusion, premorbid modified Rankin scale (mRS) of 0-3, treatment with endovascular thrombectomy and groin puncture within 12 h after stroke onset. The Maas et al., Miteff et al., Tan et al., ASITN/SIR and mCTA collateral scores were retrospectively assessed in multiphase CTA images and correlated with 90-day mRS (90d-mRS) scores. Good outcome was defined as 90d-mRS 0-2 or unchanged to premorbid mRS.
resultsIn total, 108 patients were included of which 39.8% achieved a good outcome. The area under the curve (AUC) values of receiver operating characteristic (ROC) curve analysis for Maas et al., Miteff et al., Tan et al., ASITN/SIR and mCTA scores were 0.60 (0.51-0.70), 0.60 (0.52-0.68), 0.61 (0.51-0.70), 0.59 (0.49-0.70) and 0.61 (0.50-0.71), respectively. The correlation between 90d-mRS and Maas (r = -0.16, P = 0.091), Miteff (r = -0.25, P = 0.009), Tan (r = -0.26, P = 0.007), ASITN/SIR (r = -0.21, P = 0.030) and mCTA (r = -0.22, P = 0.021) scores was poor.
conclusionAlthough collaterals are known to correlate with clinical outcome, none of the analyzed collateral scores sufficiently predicted outcome as a standalone parameter.
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