ArticleAmerican journal of epidemiology2020
Risk Prediction Models for Head and Neck Cancer in the US Population From the INHANCE Consortium.
Article in American journal of epidemiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- "We adjusted for race": now what? A systematic review of utilization and reporting of race in American Journal of Epidemiology and Epidemiology, 2020-2021.Epidemiologic reviews · 2023Pooled it
- Genetic susceptibility, risk prediction, and druggable targets for oropharyngeal cancer: a UK Biobank study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026Article
- Oral cancer large observational screening study in Hungary.European journal of public health · 2026Observational
- Oral Cancer Screening: A Biosocial Analysis of Global Barriers-A Narrative Review of Who Screens, Who Gets Screened, and Why.Cancers · 2026Review
- Knowledge-Guided Explainable Recommendation Tool for Cancer Risk Prediction Models Using Retrieval-Augmented Large Language Models: Development and Validation Study.JMIR medical informatics · 2026Article
- Role of early growth response-1 as a tumor suppressor in oral squamous cell carcinoma.Discover oncology · 2024Article
- Review
- A risk prediction model for head and neck cancers incorporating lifestyle factors, HPV serology and genetic markers.International journal of cancer · 2023Article
- Diagnostic Accuracy of an Indirect Enzyme Linked Immunosorbent Assay (iELISA) for Screening ofLife (Basel, Switzerland) · 2023Article
- Risk prediction models for head and neck cancer: A rapid review.Laryngoscope investigative otolaryngology · 2022Review
- Risk Prediction Models for Patients with Head and Neck Cancer among the Taiwanese Population.Cancers · 2022Article
- Review
- Oral Cancer Screening: Past, Present, and Future.Journal of dental research · 2021Review
- Surveillance of the Incidence and Mortality of Oral and Pharyngeal, Esophageal, and Lung Cancer in Nevada: Potential Implications of the Nevada Indoor Clean Air Act.International journal of environmental research and public health · 2021Article
- Lessons learned from the INHANCE consortium: An overview of recent results on head and neck cancer.Oral diseases · 2021Review
- Point-of-care characterization and risk-based management of oral lesions in primary dental clinics: A simulation model.PloS one · 2020Article
Corrections and comments
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Authors and funding
27 authors.
Funding
Abstract
Head and neck cancer (HNC) risk prediction models based on risk factor profiles have not yet been developed. We took advantage of the large database of the International Head and Neck Cancer Epidemiology (INHANCE) Consortium, including 14 US studies from 1981-2010, to develop HNC risk prediction models. Seventy percent of the data were used to develop the risk prediction models; the remaining 30% were used to validate the models. We used competing-risk models to calculate absolute risks. The predictors included age, sex, education, race/ethnicity, alcohol drinking intensity, cigarette smoking duration and intensity, and/or family history of HNC. The 20-year absolute risk of HNC was 7.61% for a 60-year-old woman who smoked more than 20 cigarettes per day for over 20 years, consumed 3 or more alcoholic drinks per day, was a high school graduate, had a family history of HNC, and was non-Hispanic white. The 20-year risk for men with a similar profile was 6.85%. The absolute risks of oropharyngeal and hypopharyngeal cancers were generally lower than those of oral cavity and laryngeal cancers. Statistics for the area under the receiver operating characteristic curve (AUC) were 0.70 or higher, except for oropharyngeal cancer in men. This HNC risk prediction model may be useful in promoting healthier behaviors such as smoking cessation or in aiding persons with a family history of HNC to evaluate their risks.
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