ArticleThe journal of nutrition, health & aging2019
Impact of Number of Drug Types on Clinical Outcome in Patients with Acute Hip Fracture.
Article in The journal of nutrition, health & aging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Body Mass Index Category and the Association Between Polypharmacy and Functional Recovery in Stroke Patients: A Retrospective Cohort Study.Drugs & aging · 2026Article
- Association of changes in medication with the effectiveness of rehabilitation in older patients: a hospital-based observational study.BMC geriatrics · 2026Observational
- Nonsteroidal anti-inflammatory drug use is associated with improved activities of daily living and rehabilitation in older adult patients following a fracture: a retrospective cohort study.Journal of pharmaceutical health care and sciences · 2025Article
- Polypharmacy, Potentially Inappropriate Medications, and Dysphagia in Older Inpatients: A Multi-Center Cohort Study.Annals of geriatric medicine and research · 2024Article
- Impact of the Comorbidity Polypharmacy Score on Clinical Outcome in Patients with Hip Fracture undergoing surgery Using Real-World Data.Annals of clinical epidemiology · 2023Article
- Medication regimen complexity index and rehabilitation outcomes in post-acute hip fracture patients study: a retrospective study.International journal of clinical pharmacy · 2022Article
- Association between the number of board-certified physiatrists and volume of rehabilitation provided in Japan: an ecological study.Journal of rural medicine : JRM · 2022Article
- Four Hours Postoperative Mobilization is Feasible After Thoracoscopic Anatomical Pulmonary Resection.World journal of surgery · 2021Article
- Construction and Quality Evaluation of the Japanese Sarcopenic Dysphagia Database.The journal of nutrition, health & aging · 2021Article
- Relationship between potentially inappropriate medications and functional prognosis in elderly patients with distal radius fracture: a retrospective cohort study.Journal of orthopaedic surgery and research · 2020Article
- Editorial: To Drug or Not to Drug: The Geriatrician Dilemma of Polypharmacy.The journal of nutrition, health & aging · 2020Article
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Authors and funding
4 authors.
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No grant is acknowledged in the PubMed record.
Abstract
objectivesThis study aims to investigate the impact of the number of drug types on clinical outcomes for patients with acute hip fracture. DESIGNS: This is a retrospective cross-sectional study.
settingA hospital-based database constructed by the Japan Medical Data Center.
participantsConsecutive patients exhibiting acute hip fractures on admission between April 2014 and November 2017 were included. MEASUREMENTS: Relationships among the numbers of varying drug types of ≥6 and ≤5 as well as clinical outcomes were analyzed in 11,073 patients aged ≥65 years. The primary outcome was defined as the Barthel Index efficiency, with the secondary outcome being the length of hospital stay.
resultsMedian Barthel Index scores at admission and discharge were 5 (interquartile range: 5-20) and 50 (interquartile range: 20-85). The Barthel Index efficiency was significantly higher in the group having received 5 or fewer drug variations taken (1.45 ± 1.77) than in the group receiving 6 or more drug types taken (0.94 ± 1.18) during hospital stays (p < 0.001). The length of hospital stay was significantly shorter in the group receiving 5 or fewer drug types taken (29.9 ± 23.8) than in the group having 6 or more drug types taken (44.3 ± 30.3) during hospital stays (p < 0.001), with the latter number being independently associated with the Barthel Index efficiency and length of hospital stay.
conclusionsNumber of drug types of 6 or more were associated with lower Barthel Index efficiency and longer lengths of hospital stays.
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