Trial reportJournal of diabetes research2019
Vitamin D Supplementation and Cognition in People with Type 2 Diabetes: A Randomized Control Trial.
Trial report in Journal of diabetes research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- Pooled it
- Assessing the potency of vitamin D augmentation on saccharometric indices in type 2 diabetes: a meta-analysis.Frontiers in nutrition · 2025Pooled it
- High Doses of Vitamin D and Specific Metabolic Parameters in Type 2 Diabetes Patients: Systematic Review.Nutrients · 2024Pooled it
- Effects of Vitamin D Supplementation on Cognitive Outcomes: A Systematic Review and Meta-Analysis.Neuropsychology review · 2024Pooled it
- Pooled it
- Vitamin D Supplementation and Cognition in Adults: A Systematic Review of Randomized Controlled Trials.CNS drugs · 2021Pooled it
- Effect of vitamin D on cognitive decline: results from two ancillary studies of the VITAL randomized trial.Scientific reports · 2021Trial
- Effect of Vitamin D Supplementation on Inflammatory Markers in Non-Obese Lebanese Patients with Type 2 Diabetes: A Randomized Controlled Trial.Nutrients · 2020Trial
- Dietary vitamin D intake and 2-year changes in cognitive function in older adults with overweight or obesity and metabolic syndrome.GeroScience · 2025Article
- The Potential Role of Vitamin D Supplementation in Cognitive Impairment Prevention.CNS & neurological disorders drug targets · 2024Review
- Potential role of 25(OH)D insufficiency in the dysfunction of glycolipid metabolism and cognitive impairment in patients with T2DM.Frontiers in endocrinology · 2022Article
- Article
- Promoting Successful Cognitive Aging: A Ten-Year Update.Journal of Alzheimer's disease : JAD · 2021Review
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
aimType 2 diabetes increases the risk of cognitive decline which adversely impacts self-management of the disease. Evidence also supports a relationship between low serum 25(OH)D levels and poor cognition. The purpose of this trial was to assess vitamin D supplementation on cognitive executive functioning in persons living with type 2 diabetes.
methodsThis was a double-blinded RCT where participants were randomized to receive either weekly vitamin D
resultsThirty participants were randomized to either the low-dose allocation (
conclusionsTo our knowledge, this is the first randomized control trial to examine the effects of vitamin D supplementation on cognitive function in people with type 2 diabetes. However, no significant differences in cognitive outcomes between participants who received high-dose therapy and those who received low dose were found.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.