Evidence map›Paper›PMID 31781661›Full record

ArticleJournal of diabetes research2019

The Effect of Shear Force on Skin Viability in Patients with Type 2 Diabetes.

Luuk A de Wert, Margot Geerts, Sander van der Brug, Laura Adriaansen, Martijn Poeze, Nicolaas Schaper, Nicole D Bouvy

Abstract read
In one paragraph

Article in Journal of diabetes research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Biophysical and biochemical changes in skin health of healthcare professionals using respirators during COVID-19 pandemic.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2023
    Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Luuk A de WertDepartment of General Surgery, Maastricht University Medical Centre, Maastricht, Netherlands.ORCID https://orcid.org/0000-0001-8376-2606
Margot GeertsDepartment of Neurology, Maastricht University Medical Centre, Maastricht, Netherlands.
Sander van der BrugNUTRIM School for Nutrition and Translational Research in Metabolism, Maastricht University, Maastricht, Netherlands.
Laura AdriaansenDepartment of Internal Medicine, Maastricht University Medical Centre, Maastricht, Netherlands.
Martijn PoezeDepartment of General Surgery, Maastricht University Medical Centre, Maastricht, Netherlands.
Nicolaas SchaperDepartment of Internal Medicine, Maastricht University Medical Centre, Maastricht, Netherlands.
Nicole D BouvyDepartment of General Surgery, Maastricht University Medical Centre, Maastricht, Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundShear is a major risk factor in the development of diabetic foot ulcers, but its effect on the skin of patients with type 2 diabetes mellitus (DM) remains to be elucidated. The aim was to determine skin responses to shear in DM patients with and without diabetic polyneuropathy (DNP).

methodsThe forearm skin was loaded with 14.5 N shear (+2.4 kPa pressure) and with 3.5 kPa pressure for 30 minutes in 10 type 2 DM patients without DNP, 10 type 2 DM patients with DNP, and 10 healthy participants. A Sebutape collected IL-1

findingsReactive hyperaemia and IL-1

interpretationShear is important in the development of tissue damage, but the reparative responses to shear are impaired in patients with type 2 DM. DNP was not associated with altered skin responses, suggesting that the loss of protective sensation to sense shear to skin remains a key factor in the development of diabetic foot ulcers in patients with DNP.

Indexed as

HemodynamicsMicrocirculationAdultAgedBiomarkersBlood Flow VelocityBlood GlucoseCase-Control StudiesDiabetes Mellitus, Type 2Diabetic NeuropathiesFemaleForearmHumansHyperemiaInterleukin-1alphaMaleBiomarkersBlood GlucoseIL1A protein, humanInterleukin-1alpha

Identifiers

PMID31781661
PMCPMC6875394

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.