Evidence map›Paper›PMID 31781647›Full record

ReviewBioMed research international2019

Optical Coherence Tomography of Animal Models of Retinitis Pigmentosa: From Animal Studies to Clinical Applications.

Mitsuru Nakazawa, Aiko Hara, Sei-Ichi Ishiguro

Open access · hybridAbstract readReview
In one paragraph

Review in BioMed research international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Looking for In Vitro Models for Retinal Diseases.International journal of molecular sciences · 2021
    Review
  12. The LratInternational journal of molecular sciences · 2021
    Article
  13. Article
  14. Annals of translational medicine · 2020
    Review
  15. Article
  16. Article
  17. Review
  18. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Mitsuru NakazawaDepartment of Ophthalmology, Hirosaki University Graduate School of Medicine, Hirosaki, Japan.ORCID https://orcid.org/0000-0001-6095-5712
Aiko HaraDepartment of Ophthalmology, Hirosaki University Graduate School of Medicine, Hirosaki, Japan.
Sei-Ichi IshiguroDepartment of Ophthalmology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Hirosaki University · JPTohoku University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of this study was to understand the relationship between the findings of spectral-domain optical coherence tomography (SD-OCT) of previously reported animal models of retinitis pigmentosa (RP) associated with known genetic mutations and their background structural and functional changes.

methodsWe reviewed previous publications reporting the SD-OCT findings of animal models of RP and summarized the characteristic findings of SD-OCT in nine different animal models (

resultsDespite the various abnormal structural changes found in these different animal models, progressive thinning of the outer nuclear layer (ONL) and hyperreflective change in the inner and outer segment (IS-OS) layers of the photoreceptors were commonly observed on SD-OCT. In the rapidly progressive severe photoreceptor degeneration seen in rd10 and

Indexed as

Disease Models, AnimalAnimalsArrestinscis-trans-IsomerasesCyclic Nucleotide Phosphodiesterases, Type 6HumansMiceMice, KnockoutRatsRats, TransgenicRetinaRetinal DegenerationRetinitis PigmentosaRetinoid IsomerohydrolaseRhodopsinTomography, Optical Coherencearrestin 1 protein, mouseArrestinscis-trans-IsomerasesCyclic Nucleotide Phosphodiesterases, Type 6Pde6b protein, mouseRetinoid IsomerohydrolaseRhodopsin

Identifiers

PMID31781647
PMCPMC6875330
OpenAlexW2982411379

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.