Evidence map›Paper›PMID 31781638›Full record

ArticleBioMed research international2019

Adipokine Chemerin Stimulates Progression of Atherosclerosis in ApoE

Huadong Liu, Wei Xiong, Yu Luo, Hua Chen, Yaqiong He, Yuanzhi Cao, Shaohong Dong

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 27 citations in OpenAlex.

  1. Review
  2. Chemerin/ChemerinR1 axis and inflammation-related diseases.Frontiers in molecular biosciences · 2026
    Review
  3. Review
  4. Adipokines: masterminds of metabolic inflammation.Nature reviews. Immunology · 2025
    Review
  5. Article
  6. Article
  7. Review
  8. Adipokines, adiposity, and atherosclerosis.Cellular and molecular life sciences : CMLS · 2022
    Review
  9. Article
  10. Review
  11. Article
  12. Inflammatory Mediators in Atherosclerotic Vascular Remodeling.Frontiers in cardiovascular medicine · 2022
    Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Adipokines and Inflammation: Focus on Cardiovascular Diseases.International journal of molecular sciences · 2020
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Huadong LiuDepartment of Cardiology, Shenzhen People's Hospital, The Second Affiliated Hospital of Jinan Medical College, Shenzhen 518020, China.
Wei XiongDepartment of Cardiology, Shenzhen People's Hospital, The Second Affiliated Hospital of Jinan Medical College, Shenzhen 518020, China.
Yu LuoDepartment of Gerontology, Shenzhen People's Hospital, The Second Affiliated Hospital of Jinan Medical College, Shenzhen 518020, China.
Hua ChenDepartment of Emergency, Shenzhen People's Hospital, The Second Affiliated Hospital of Jinan Medical College, Shenzhen 518020, China.
Yaqiong HeDepartment of Cardiology, Shenzhen People's Hospital, The Second Affiliated Hospital of Jinan Medical College, Shenzhen 518020, China.
Yuanzhi CaoDepartment of Cardiology, Shenzhen People's Hospital, The Second Affiliated Hospital of Jinan Medical College, Shenzhen 518020, China.
Shaohong DongDepartment of Cardiology, Shenzhen People's Hospital, The Second Affiliated Hospital of Jinan Medical College, Shenzhen 518020, China.ORCID https://orcid.org/0000-0002-8019-1884
Jinan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVascular remodeling is the most critical pathogenesis of atherosclerosis. Adipokine chemerin was known for its relationship with obesity as well as metabolism. Most recently, chemerin was found to play a crucial role in the pathologic process of cardiovascular diseases including coronary heart disease. In this study, we surveyed the role of chemerin in progression of atherosclerosis in ApoE

objectiveTo investigate the relationship between chemerin and progression of atherosclerosis in ApoE

methods8-week-old ApoE

resultAortic plaque formation was significantly induced by high-fat diet in ApoE

conclusionOur study revealed that chemerin stimulated the progression of atherosclerosis in ApoE

Indexed as

MAP Kinase Signaling SystemAdipokinesAnimalsAortaAtherosclerosisChemokinesDietary FatsIntercellular Signaling Peptides and ProteinsInterleukin-1betaMiceMice, Knockout, ApoEPlaque, AtheroscleroticTransforming Growth Factor beta1Tumor Necrosis Factor-alphaVascular RemodelingAdipokineschemerin protein, mouseChemokinesDietary FatsIL1B protein, mouseIntercellular Signaling Peptides and ProteinsInterleukin-1betaTgfb1 protein, mouseTransforming Growth Factor beta1Tumor Necrosis Factor-alpha

Identifiers

PMID31781638
PMCPMC6875193
OpenAlexW2982622042

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.