Evidence map›Paper›PMID 31781629›Full record

ArticleBioMed research international2019

Assessment of Serum Concentrations of Adropin, Afamin, and Neudesin in Children with Type 1 Diabetes.

Agnieszka Polkowska, Izabela Elżbieta Pasierowska, Marta Pasławska, Elżbieta Pawluczuk, Artur Bossowski

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Serum Neudesin Levels in Patients with Congenital HypothyroidismJournal of clinical research in pediatric endocrinology · 2025
    Article
  3. Article
  4. Article
  5. Preclinical Serological Signatures are Associated With Complicated Crohn's Disease Phenotype at Diagnosis.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2023
    Article
  6. Article
  7. Article
  8. Adropin's Role in Energy Homeostasis and Metabolic Disorders.International journal of molecular sciences · 2022
    Review
  9. Serum Neudesin Levels in Obese AdolescentsJournal of clinical research in pediatric endocrinology · 2022
    Article
  10. Review of Novel Potential Insulin Resistance Biomarkers in PCOS Patients-The Debate Is Still Open.International journal of environmental research and public health · 2022
    Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Agnieszka PolkowskaDepartment of Pediatrics, Endocrinology, Diabetology with Subdivision of Cardiology, Medical University of Białystok, Białystok, Poland.ORCID https://orcid.org/0000-0002-2803-9527
Izabela Elżbieta PasierowskaDepartment of Pediatrics, Endocrinology, Diabetology with Subdivision of Cardiology, Medical University of Białystok, Białystok, Poland.ORCID https://orcid.org/0000-0002-3968-170X
Marta PasławskaDepartment of Pediatrics, Endocrinology, Diabetology with Subdivision of Cardiology, Medical University of Białystok, Białystok, Poland.
Elżbieta PawluczukDepartment of Pediatrics, Endocrinology, Diabetology with Subdivision of Cardiology, Medical University of Białystok, Białystok, Poland.
Artur BossowskiDepartment of Pediatrics, Endocrinology, Diabetology with Subdivision of Cardiology, Medical University of Białystok, Białystok, Poland.ORCID https://orcid.org/0000-0002-6316-5342
Medical University of Białystok · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe increasing knowledge of adropin, afamin, and neudesin and the regulation of glucose metabolism and insulin resistance allows for the assessment of the differences in their concentrations between the groups with varied duration of diabetes mellitus (DM). AIM OF THE STUDY: Assessment of serum levels of adropin, afamin, and neudesin in children with type 1 diabetes, with respect to the disease duration. MATERIALS AND

methodsThe study consisted of 138 patients aged 5-18 years (M 40.58%). Children with type 1 diabetes (

resultsThe concentrations of adropin and afamin across all subgroups were lower than that in the control group, while neudesin levels were higher in diabetic patients compared to the control group. The differences were statistically significant.

conclusionsAdropin, afamin, and neudesin may play a major role in the regulation of glucose metabolism and have a significant potential as novel biomarkers to predict future metabolic disorders. However, further multicentre studies on a larger cohort of patients are necessary to specify the role of these substances in the course and treatment of type 1 diabetes.

Indexed as

AdolescentBiomarkersBlood ProteinsCarrier ProteinsChildChild, PreschoolDiabetes Mellitus, Type 1FemaleGlucoseGlycated HemoglobinGlycoproteinsHumansIntercellular Signaling Peptides and ProteinsKetosisMaleMetabolic DiseasesAFM protein, humanBiomarkersBlood ProteinsCarrier ProteinsEnho protein, humanGlucoseGlycated HemoglobinGlycoproteinshemoglobin A1c protein, humanIntercellular Signaling Peptides and ProteinsNENF protein, humanNerve Tissue ProteinsSerum Albumin, Human

Identifiers

PMID31781629
PMCPMC6855013
OpenAlexW2981865417

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.