Evidence map›Paper›PMID 31781574›Full record

ArticleFrontiers in molecular biosciences2019

Maxim Shkurnikov, Sergey Nikulin, Stepan Nersisyan, Andrey Poloznikov, Shan Zaidi, Ancha Baranova, Udo Schumacher, Daniel Wicklein, Alexander Tonevitsky

Open access · goldAbstract read
In one paragraph

Article in Frontiers in molecular biosciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 8 institutions in 3 countries.

Maxim ShkurnikovNational Medical Research Radiological Center, Ministry of Health of the Russian Federation, Obninks, Russia.
Sergey NikulinFar Eastern Federal University, Vladivostok, Russia.
Stepan NersisyanFaculty of Mechanics and Mathematics, Lomonosov Moscow State University, Moscow, Russia.
Andrey PoloznikovNational Medical Research Radiological Center, Ministry of Health of the Russian Federation, Obninks, Russia.
Shan ZaidiSchool of Systems Biology, George Mason University, Fairfax, VA, United States.
Ancha BaranovaSchool of Systems Biology, George Mason University, Fairfax, VA, United States.
Udo SchumacherInstitute of Anatomy and Experimental Morphology, University Cancer Center, University Medical-Center Hamburg-Eppendorf, Hamburg, Germany.
Daniel WickleinInstitute of Anatomy and Experimental Morphology, University Cancer Center, University Medical-Center Hamburg-Eppendorf, Hamburg, Germany.
Alexander TonevitskyFaculty of Biology and Biotechnologies, Higher School of Economics, Moscow, Russia.
George Mason University · USFar Eastern Federal University · RUInstitute of Bioorganic Chemistry · RULomonosov Moscow State University · RUMedical Radiological Research Center · RUMinistry of Health of the Russian Federation · RUUniversität Hamburg · DEUniversity Cancer Center Hamburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Specificity of RNAi to selected target is challenged by off-target effects, both canonical and non-canonical. Notably, more than half of all human microRNAs are co-expressed with hosting them proteincoding genes. Here we dissect regulatory subnetwork centered on

Indexed as

breast cancerintragenic miRNAlamininsmiRNATCGA

Identifiers

PMID31781574
PMCPMC6857517
OpenAlexW2984939860

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.