Evidence map›Paper›PMID 31781462›Full record

ArticleCase reports in rheumatology2019

A Case of Severe Seronegative Inflammatory Arthritis due to Nivolumab and Review of the Literature.

Bicky Thapa, Asad Ali, Raunak Nair, Rishik Vashisht, Cassandra Calabrese

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Case reports in rheumatology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Bicky ThapaDepartment of Internal Medicine, Cleveland Clinic Fairview Hospital, Cleveland, Ohio, USA.ORCID https://orcid.org/0000-0002-7636-8907
Asad AliNeurological Institute, Taussig Center Institute, Cleveland Clinic Foundation, Cleveland, Ohio, USA.
Raunak NairDepartment of Internal Medicine, Cleveland Clinic Fairview Hospital, Cleveland, Ohio, USA.
Rishik VashishtRespiratory Institute, Cleveland Clinic Foundation, Cleveland, Ohio, USA.
Cassandra CalabreseDepartment of Rheumatic & Immunologic Disease, Cleveland Clinic Foundation, Cleveland, Ohio, USA.ORCID https://orcid.org/0000-0002-8773-7739

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immune-checkpoint inhibitors (ICIs) have revolutionized the treatment of cancer, yet therapy is often hampered by immune-related adverse events (irAEs) which range from mild to severe life-threatening events. Musculoskeletal (MSK) irAEs leading to discontinuation of ICIs are uncommon but increasingly recognized. We report a challenging case of severe immune-related seronegative inflammatory arthritis due to nivolumab in a patient with stage IV metastatic adenocarcinoma.

Identifiers

PMID31781462
PMCPMC6875374

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.