Evidence map›Paper›PMID 31781357›Full record

ArticleOxidative medicine and cellular longevity2019

Corn Silk (

Mai M Al-Oqail, Ebtesam S Al-Sheddi, Nida N Farshori, Shaza M Al-Massarani, Eman A Al-Turki, Javed Ahmad, Abdulaziz A Al-Khedhairy, Maqsood A Siddiqui

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
7.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 43 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. In Vitro Analysis of Cytotoxic Activities ofPlants (Basel, Switzerland) · 2023
    Article
  6. Article
  7. Inhibitory effects of probioticIranian journal of microbiology · 2021
    Article
  8. Article
  9. Anticancer efficacies ofSaudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2021
    Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Mai M Al-OqailDepartment of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Ebtesam S Al-SheddiDepartment of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Nida N FarshoriDepartment of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.ORCID https://orcid.org/0000-0003-1310-3351
Shaza M Al-MassaraniDepartment of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.ORCID https://orcid.org/0000-0002-6298-7205
Eman A Al-TurkiDepartment of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Javed AhmadAl-Jeraisy Chair for DNA Research, Zoology Department, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia.
Abdulaziz A Al-KhedhairyZoology Department, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia.
Maqsood A SiddiquiAl-Jeraisy Chair for DNA Research, Zoology Department, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia.ORCID https://orcid.org/0000-0002-2010-3088
King Saud University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer has been recognized as one of the life-threating diseases. Breast cancer is a leading cause of mortality among women. In spite of current developments in the therapy and diagnosis of cancer, the survival rate is still less. Recently, plant-derived natural products gain attention as anticancer agents due to the nontoxic nature. Therefore, the aim of present study was to investigate the anticancer capacity of corn silk extract (CSE) on human breast cancer (MCF-7) and normal human mesenchymal (hMSC-TERT4) cells. Following 24 h treatment to corn silk extract, the cytotoxicity was assessed by MTT, NRU, and morphological assays. The oxidative stress markers (GSH and LPO), ROS production, MMP change, and expression of apoptotic marker genes (p53, Bax, Bcl-2, caspase-3, and caspase-9) were also studied in MCF-7 cells treated at 250 to 1000

Indexed as

Breast NeoplasmsApoptosisFemaleGene Expression Regulation, NeoplasticHumansMCF-7 CellsMitochondriaNeoplasm ProteinsPlant ProteinsReactive Oxygen SpeciesSignal TransductionUp-RegulationZea maysNeoplasm ProteinsPlant ProteinsReactive Oxygen Species

Identifiers

PMID31781357
PMCPMC6855084
OpenAlexW2980560484

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.