Evidence map›Paper›PMID 31781354›Full record

ArticleOxidative medicine and cellular longevity2019

Modified Huang-Lian-Jie-Du Decoction Ameliorates A

Yan Liu, Ting Du, Wenlong Zhang, Weiye Lu, Zhichao Peng, Shuqiong Huang, Xiangdong Sun, Xiaoqin Zhu, Chaojun Chen, Linchao Qian and 3 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oxidative medicine and cellular longevity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 41 citations in OpenAlex.

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  18. Role of Aβ in Alzheimer's-related synaptic dysfunction.Frontiers in cell and developmental biology · 2022
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  19. Therapeutic effects of total saikosaponins fromFrontiers in pharmacology · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 1 country.

Yan LiuKey Laboratory of Neuroscience, School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou 511436, China.ORCID https://orcid.org/0000-0001-7891-971X
Ting DuDepartment of Traditional Chinese Medicine, School of Medicine, Xiamen University, Xiamen 361102, China.ORCID https://orcid.org/0000-0002-0959-0532
Wenlong ZhangKey Laboratory of Neuroscience, School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou 511436, China.
Weiye LuKey Laboratory of Neuroscience, School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou 511436, China.
Zhichao PengDepartment of Neurology, Guangzhou Chinese Medical Integrated Hospital (Huadu), Guangdong 510800, China.ORCID https://orcid.org/0000-0003-4473-9280
Shuqiong HuangDepartment of Traditional Chinese Medicine, School of Medicine, Xiamen University, Xiamen 361102, China.ORCID https://orcid.org/0000-0002-4276-539X
Xiangdong SunSchool of Basic Medical Sciences, Second Affiliated Hospital of Guangzhou Medical University, Guangzhou 510260, China.ORCID https://orcid.org/0000-0002-0051-1463
Xiaoqin ZhuGuangzhou Medical University, Guangzhou 511436, China.ORCID https://orcid.org/0000-0002-2801-1217
Chaojun ChenDepartment of Neurology, Guangzhou Chinese Medical Integrated Hospital (Huadu), Guangdong 510800, China.ORCID https://orcid.org/0000-0003-0881-6242
Linchao QianDepartment of Traditional Chinese Medicine, School of Medicine, Xiamen University, Xiamen 361102, China.ORCID https://orcid.org/0000-0002-4825-0725
Lei WenDepartment of Traditional Chinese Medicine, School of Medicine, Xiamen University, Xiamen 361102, China.ORCID https://orcid.org/0000-0002-9610-655X
Pingyi XuDepartment of Neurology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.ORCID https://orcid.org/0000-0001-8716-5892
Yunlong ZhangKey Laboratory of Neuroscience, School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou 511436, China.ORCID https://orcid.org/0000-0002-2447-9138
Xiamen University · CNGuangzhou Medical University · CNIntegrated Chinese Medicine (China) · CNFirst Affiliated Hospital of Guangzhou Medical University · CNSecond Affiliated Hospital of Guangzhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alzheimer's disease (AD) is a common neurodegenerative disease, characterized by cognitive dysfunction; however, the therapeutic strategies are not fully understood. Huang-Lian-Jie-Du-Decoction (HLJDD) is a famous traditional Chinese herbal formula that has been widely used clinically to treat dementia. Recently, according to previous study and our clinical practice, we generate a new modification of HLJDD (named modified-HLJDD). In this study, we indicated that modified-HLJDD attenuated learning and memory deficiencies in A

Indexed as

Alzheimer DiseaseAmyloid beta-PeptidesAnimalsAnti-Inflammatory Agents, Non-SteroidalDisease Models, AnimalDrugs, Chinese HerbalHumansMaleMiceNeuronal PlasticityPeptide FragmentsSynapsesSynaptic TransmissionAmyloid beta-Peptidesamyloid beta-protein (1-42)Anti-Inflammatory Agents, Non-SteroidalDrugs, Chinese Herbaloren gedoku toPeptide Fragments

Identifiers

PMID31781354
PMCPMC6875425
OpenAlexW2989330157

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.