Evidence map›Paper›PMID 31781347›Full record

Trial reportOxidative medicine and cellular longevity2019

Relationships between Ghrelin and Obestatin with MDA, Proinflammatory Cytokines, GSH/GSSG Ratio, Catalase Activity, and Semen Parameters in Infertile Patients with Leukocytospermia and Varicocele.

Lucia Micheli, Giulia Collodel, Daniela Cerretani, Andrea Menchiari, Daria Noto, Cinzia Signorini, Elena Moretti

Open access · hybridAbstract readClinical Trial
In one paragraph

Trial report in Oxidative medicine and cellular longevity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Potentiality of ghrelin as antioxidant and protective agent.Redox report : communications in free radical research · 2021
    Pooled it
  3. Review
  4. Advances in immunological research on male infertility.Frontiers in reproductive health · 2026
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
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  13. Review
  14. Article
  15. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Lucia MicheliDepartment of Medical and Surgical Sciences and Neurosciences, University of Siena, Siena, Italy.ORCID https://orcid.org/0000-0002-0306-9308
Giulia CollodelDepartment of Molecular and Developmental Medicine, University of Siena, Siena, Italy.ORCID https://orcid.org/0000-0003-1587-0159
Daniela CerretaniDepartment of Medical and Surgical Sciences and Neurosciences, University of Siena, Siena, Italy.ORCID https://orcid.org/0000-0001-9498-1644
Andrea MenchiariDepartment of Business and Law, University of Siena, Siena, Italy.
Daria NotoDepartment of Molecular and Developmental Medicine, University of Siena, Siena, Italy.ORCID https://orcid.org/0000-0002-1571-9056
Cinzia SignoriniDepartment of Molecular and Developmental Medicine, University of Siena, Siena, Italy.ORCID https://orcid.org/0000-0003-0006-9414
Elena MorettiDepartment of Molecular and Developmental Medicine, University of Siena, Siena, Italy.ORCID https://orcid.org/0000-0002-9467-0501
University of Siena · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ghrelin and obestatin are involved in many biological functions including reproduction. Growing evidences suggest that both peptides could exert protective and antioxidant activities. In this study, the relationships between ghrelin/obestatin, interleukin-6 (IL-6), tumor necrosis factor-

Indexed as

AdultCatalaseGhrelinGlutathione DisulfideHumansInfertility, MaleInterleukin-6MaleSemenTumor Necrosis Factor-alphaVaricoceleCatalaseGhrelinGlutathione DisulfideIL6 protein, humanInterleukin-6obestatin, humanTumor Necrosis Factor-alpha

Identifiers

PMID31781347
PMCPMC6855048
OpenAlexW2980828919

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.