Evidence map›Paper›PMID 31781202›Full record

ArticleJournal of toxicology2019

Lyophilized

B Appala Naidu, Kamala Kannan, D P Santhosh Kumar, John W K Oliver, Zachary D Abbott

Open access · goldAbstract read
In one paragraph

Article in Journal of toxicology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.3field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 21 citations in OpenAlex.

  1. Trial
  2. Review
  3. Review
  4. Article
  5. EngineeredACS synthetic biology · 2025
    Article
  6. Review
  7. Article
  8. Article
  9. EngineeredbioRxiv : the preprint server for biology · 2024
    Article
  10. Article
  11. Article
  12. Engineering bacteria to modulate host metabolism.Acta physiologica (Oxford, England) · 2023
    Review
  13. Engineered probiotics.Microbial cell factories · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

B Appala NaiduDepartment of Safety Assessment, Eurofins Advinus Limited, Post Box No. 5813, Plot Nos. 21 & 22 Peenya II Phase, Bengaluru 560 058, India.
Kamala KannanDepartment of Safety Assessment, Eurofins Advinus Limited, Post Box No. 5813, Plot Nos. 21 & 22 Peenya II Phase, Bengaluru 560 058, India.
D P Santhosh KumarDepartment of Safety Assessment, Eurofins Advinus Limited, Post Box No. 5813, Plot Nos. 21 & 22 Peenya II Phase, Bengaluru 560 058, India.
John W K OliverZBiotics Company, 181 2nd St., San Francisco, CA 94105, USA.
Zachary D AbbottZBiotics Company, 181 2nd St., San Francisco, CA 94105, USA.ORCID https://orcid.org/0000-0001-9859-078X
AvidBiotics (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 90-day repeated-dose oral toxicological evaluation was conducted according to GLP and OECD guidelines on lyophilized spores of the novel genetically modified strain

Identifiers

PMID31781202
PMCPMC6875028
OpenAlexW2986220483

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.