Evidence map›Paper›PMID 31781104›Full record

ArticleFrontiers in immunology2019

Lipocalin 2 Protects Against

Qianqian Wang, Shuhui Li, Xueyou Tang, Li Liang, Fengqin Wang, Huahua Du

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 60 citations in OpenAlex.

  1. Trial
  2. Review
  3. Review
  4. The osteoclast intracellular environment fosters bacterial growth duringbioRxiv : the preprint server for biology · 2026
    Article
  5. Review
  6. Review
  7. Observational
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Lipocalin-2 and intestinal diseases.World journal of gastroenterology · 2024
    Review
  14. Article
  15. CXCR2 perturbation promotesJournal of medical microbiology · 2024
    Article
  16. Review
  17. Article
  18. Article
  19. The regulation of TRPA1 expression and function by Th1 and Th2-type inflammation in human A549 lung epithelial cells.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Qianqian WangMoE Key Laboratory of Molecular Animal Nutrition, College of Animal Sciences, Zhejiang University, Hangzhou, China.
Shuhui LiMoE Key Laboratory of Molecular Animal Nutrition, College of Animal Sciences, Zhejiang University, Hangzhou, China.
Xueyou TangMoE Key Laboratory of Molecular Animal Nutrition, College of Animal Sciences, Zhejiang University, Hangzhou, China.
Li LiangMoE Key Laboratory of Molecular Animal Nutrition, College of Animal Sciences, Zhejiang University, Hangzhou, China.
Fengqin WangMoE Key Laboratory of Molecular Animal Nutrition, College of Animal Sciences, Zhejiang University, Hangzhou, China.
Huahua DuMoE Key Laboratory of Molecular Animal Nutrition, College of Animal Sciences, Zhejiang University, Hangzhou, China.
Zhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lipocalin 2 (Lcn2) is an essential component of the antimicrobial innate immune system. It attenuates bacterial growth by binding and sequestering the iron-scavenging siderophores to prevent bacterial iron acquisition. Whereas, the ability of Lcn2 to sequester iron is well-described, the role of Lcn2 in regulating immune cells during bacterial infection remains unclear. In this study, we showed that upon infection with

Indexed as

AnimalsCell MovementChemotaxis, LeukocyteCytokinesEscherichia coli InfectionsEscherichia coli O157Host Microbial InteractionsImmunity, InnateLipocalin-2MacrophagesMaleMiceMice, Inbred C57BLMice, KnockoutNeutrophilsPhagocytosisCytokinesLcn2 protein, mouseLipocalin-2bacterial challengeLcn2-deficient micelipocalin 2macrophageneutrophil

Identifiers

PMID31781104
PMCPMC6857527
OpenAlexW2986024416

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.