Evidence map›Paper›PMID 31781098›Full record

ArticleFrontiers in immunology2019

Assessing the Correlation Between Disease Severity Indices and Quality of Life Measurement Tools in Pemphigus.

Rebecca L Krain, Carolyn J Kushner, Meera Tarazi, Rebecca G Gaffney, Andrea C Yeguez, Danielle E Zamalin, David R Pearson, Rui Feng, Aimee S Payne, Victoria P Werth

Abstract read
In one paragraph

Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Rebecca L KrainCorporal Michael J. Crescenz VA Medical Center, Philadelphia, PA, United States.
Carolyn J KushnerCorporal Michael J. Crescenz VA Medical Center, Philadelphia, PA, United States.
Meera TaraziCorporal Michael J. Crescenz VA Medical Center, Philadelphia, PA, United States.
Rebecca G GaffneyCorporal Michael J. Crescenz VA Medical Center, Philadelphia, PA, United States.
Andrea C YeguezCorporal Michael J. Crescenz VA Medical Center, Philadelphia, PA, United States.
Danielle E ZamalinCorporal Michael J. Crescenz VA Medical Center, Philadelphia, PA, United States.
David R PearsonCorporal Michael J. Crescenz VA Medical Center, Philadelphia, PA, United States.
Rui FengDepartment of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, PA, United States.
Aimee S PayneDepartment of Dermatology, University of Pennsylvania, Philadelphia, PA, United States.
Victoria P WerthCorporal Michael J. Crescenz VA Medical Center, Philadelphia, PA, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pemphigus, an autoimmune blistering disease that affects the skin and mucous membranes, adversely impacts patients' quality of life (QOL). While there are various QOL measurement tools that can be used in this disease, few studies have assessed how a patient's change in disease severity can affect their QOL. This study aims to identify which disease severity index correlates best with the change in QOL. Fifty pemphigus patients completed QOL surveys with disease severity scored over two visits. QOL was assessed with the Autoimmune Bullous Disease Quality of Life (ABQOL), Dermatology Life Quality Index (DLQI), Skindex-29, and Short Form Survey 36 (SF-36). Disease severity was scored with the Pemphigus Disease Area Index (PDAI) and Autoimmune Bullous Skin Disorder Intensity Score (ABSIS). Correlations between the change in QOL scores and change in disease severity were analyzed using Spearman's coefficient (

Indexed as

Quality of LifeAdultAgedBiopsyDisease SusceptibilityFemaleHumansMaleMiddle AgedPatient Outcome AssessmentPemphigusPublic Health SurveillanceSeverity of Illness IndexSymptom Assessmentautoimmune bullous diseaseautoimmunitydermatologydisease severityoutcome measurespemphigusskin

Identifiers

PMID31781098
PMCPMC6851056

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.