ReviewFrontiers in psychiatry2019
Pathways Relating the Neurobiology of Attachment to Drug Addiction.
Review in Frontiers in psychiatry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02979093 (Oxytocin and Brain Reward and Stress Responses to Infant Cues in Addicted Mothers), which is not on this map. Cited by 28 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Oxytocin and Brain Reward and Stress Responses to Infant Cues in Addicted Mothers
Who cites it
28 citing papers in PubMed, 66 citations in OpenAlex.
- A bibliometric analysis of research on child development and digital addiction.Discover mental health · 2026Article
- The unique contributions of adverse childhood experiences to increases in post-traumatic stress symptoms and problematic substance use after trauma exposure.Scientific reports · 2026Article
- Infant Caregiving as a Resilience Factor for Postpartum Substance Misuse: A Scoping Review.Adversity and resilience science · 2026Review
- Adverse childhood experiences as predictors of alcohol and tobacco addiction risk among college students in Delhi-NCR, India.Scientific reports · 2025Article
- Multi-omics Analysis Reveals miR-7220-5p Alleviates NThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Fathers' Cocaine Use and Parent-Child Feeding Interactions.Journal of clinical medicine · 2025Article
- Underexplored Connections Between Diabetes, Hypomanic States and Insecure Attachment.Psychology research and behavior management · 2025Review
- Trajectories of changes in oxytocin and vasopressin before, during, and after mother-infant interaction: a descriptive study of mothers and infants affected by postpartum depression.Frontiers in psychiatry · 2025Article
- Measuring attraction to screen devices in early childhood: development of the Affinity-TV and Affinity-Mobile scales.Frontiers in pediatrics · 2025Article
- Effects of insecure attachment on fMRI resting state functional connectivity in poly drug use disorder.PloS one · 2025Observational
- Metabolomic Profile Modification in the Cerebellum of Mice Repeatedly Exposed to Khat and Treated with β-Lactamase Inhibitor, Clavulanic Acid.Metabolites · 2024Article
- Neural correlates of altered emotional responsivity to infant stimuli in mothers who use substances.Journal of psychiatric research · 2024Article
- Oxytocin as a physiological correlate of dyadic music therapy relationships - a randomized crossover pilot study.Frontiers in behavioral neuroscience · 2024Article
- Commentary: Improving the Effectiveness and Utility of the Helping to End Addiction Long-Term (HEAL) Prevention Cooperative: A Full Translational Framework.Prevention science : the official journal of the Society for Prevention Research · 2023Article
- Gambling: Exploring the Role of Gambling Motives, Attachment and Addictive Behaviours Among Adolescents and Young Women.Journal of gambling studies · 2023Article
- [Comorbidity of posttraumatic stress disorder and addiction from a biopsychosocial perspective].Neuropsychiatrie : Klinik, Diagnostik, Therapie und Rehabilitation : Organ der Gesellschaft Osterreichischer Nervenarzte und Psychiater · 2022Article
- Prenatal Reflective Functioning as a Predictor of Substance-Using Mothers' Treatment Outcome: Comparing Results From Two Different RF Measures.Frontiers in psychology · 2022Article
- "I Grew Up Amidst Alcohol and Drugs:" a Qualitative Study on the Lived Experiences of Parental Substance Use Among Adults Who Developed Substance Use Disorders Themselves.Frontiers in psychiatry · 2022Article
- Parenting and addictions: Current insights from human neuroscience.Current addiction reports · 2021Article
- Effect of early life social adversity on drug abuse vulnerability: Focus on corticotropin-releasing factor and oxytocin.Neuropharmacology · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 4 institutions in 1 country.
Funding
Abstract
Substance use disorders constitute a significant public health problem in North America and worldwide. Specifically, substance addictions in women during pregnancy or in the postpartum period have adverse effects not only on the mother, but also on mother-infant attachment and the child's subsequent development. Additionally, there is growing evidence suggesting that parental addiction may be transmitted intergenerationally, where the child of parents with addiction problems is more likely to experience addiction as an adult. The current review takes a developmental perspective and draws from animal and human studies to examine how compromised early experience, including insecure attachment, early abuse/neglect, and unresolved trauma, may influence the development of neurobiological pathways associated with addictions, ultimately increasing one's susceptibility to addictions later in life. We approach this from three different levels: molecular, neuroendocrine and behavioral; and examine the oxytocin affiliation system, dopamine reward system, and glucocorticoid stress response system in this regard. Increased understanding of these underlying mechanisms may help identify key targets for early prevention efforts and inform needed intervention strategies related to both insecure attachment and addiction.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.