ReviewFrontiers in neuroscience2019
Inappropriate Antidiuretic Hormone Secretion and Cerebral Salt-Wasting Syndromes in Neurological Patients.
Review in Frontiers in neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04744987 (Changes in Serum Creatinine Levels Can Help Distinguish Hypovolemic From Euvolemic Hyponatremia), which is not on this map. Cited by 52 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Changes in Serum Creatinine Levels Can Help Distinguish Hypovolemic From Euvolemic Hyponatremia
Who cites it
52 citing papers in PubMed, 1 synthesis or guideline pooled it, 103 citations in OpenAlex.
- Association of hyponatremia and risk of in-hospital mortality in patients with acute stroke: a systematic review and meta-analysis.Frontiers in stroke · 2026Pooled it
- Development and Internal Validation of a Preliminary Risk Prediction Model for Delayed Posthemorrhagic Hydrocephalus in Patients with Intraventricular Hemorrhage.Neurocritical care · 2026Article
- Distinguishing Between SIAD and Cerebral Salt Wasting: Is Dynamic Copeptin Response the Answer?Indian journal of pediatrics · 2026Article
- Article
- Article
- Multiple endocrine neoplasia with an atypical clinical course and a MEN1 gene variant of uncertain pathogenicity: A case report.Medicine · 2026Article
- Fever and syndrome of inappropriate antidiuretic hormone secretion in a patient with multiple system atrophy after treatment with duloxetine.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026Article
- Clinical profile and predictors of guillain-barre syndrome associated pneumonia: a retrospective cohort study.BMC neurology · 2026Article
- Sodium and Water Homeostasis in Children: Pathogenesis, Diagnosis, and Treatment.Journal of clinical medicine · 2026Review
- Improvement in post-hemispherotomy cerebral salt-wasting syndrome following intubation: A case report.Clinical pediatric endocrinology : case reports and clinical investigations : official journal of the Japanese Society for Pediatric Endocrinology · 2026Article
- Cerebral salt wasting syndrome in an elderly patient with traumatic brain injury: a case report.Frontiers in medicine · 2026Article
- Hydrocortisone versus dexamethasone in cerebral salt-wasting after aneurysmal subarachnoid hemorrhage.Brain & spine · 2026Article
- Severe hyponatremia masking cryptococcal meningitis in a fingolimod-treated patient: a case report.AME case reports · 2026Article
- Hydroelectrolytic syndromes in neuroanesthesia and neurocritical care.World journal of critical care medicine · 2025Review
- Hyponatremia in Acute Stroke: A Comparative Study of Ischemic and Hemorrhagic Stroke Subtypes.Cureus · 2025Article
- Hyponatremia Due to VZV-Induced SIADH in an Older Patient: Case Report and Literature Review.Infectious disease reports · 2025Article
- Multiphase management of sodium imbalance following traumatic brain injury: a case-based review.BMC pediatrics · 2025Review
- Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH) Triggered by Heat Stroke: A Case Report.Cureus · 2025Article
- A case ofNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025Article
- Case Report: Presumed cerebral salt wasting syndrome in a 10-week-old German Shorthaired Pointer.Frontiers in veterinary science · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The differential diagnosis of syndrome of inappropriate antidiuretic hormone secretion (SIADH) and cerebral salt-wasting syndrome (CSWS) in patients with neurological disorders has been a perplexing clinical controversy. The purpose of this review is to summarize the characteristics and risk factors of patients with different types of neurological disorders complicated by hyponatremia (HN) and review various methods to distinguish SIADH from CSWS. Common neurological disorders with high rates of HN include subarachnoid hemorrhage (SAH), traumatic brain injuries, stroke, cerebral tumors, central nervous system (CNS) infections, and Guillain-Barré syndrome (GBS), which have their own characteristics. Extracellular volume (ECV) status of patients is a key point to differentiate SIADH and CSWS, and a comprehensive assessment of relevant ECV indicators may be useful in differentiating these two syndromes. Besides, instead of monitoring the urinary sodium excretion, more attention should be paid to the total mass balance, including Na
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.