ArticleScientific reports2019
Mechanical properties of the shoulder and pectoralis major in breast cancer patients undergoing breast-conserving surgery with axillary surgery and radiotherapy.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 35 citations in OpenAlex.
- The effects of the mirror therapy on shoulder function in patients with breast cancer following surgery: a randomized controlled trial.Journal of cancer survivorship : research and practice · 2024Trial
- Body Composition and Pectoralis Major Muscle Evaluation in Women Undergoing Breast Cancer Surgery: A Longitudinal Preliminary Observational Study.Muscles (Basel, Switzerland) · 2026Article
- Impact of excluding internal mammary node coverage on musculoskeletal dosimetry in breast radiotherapy.Clinical and translational radiation oncology · 2026Article
- Manual therapy considerations for adhesive capsulitis in the breast cancer population: a clinical perspective.The Journal of manual & manipulative therapy · 2025Article
- Effect of Prepectoral Versus Subpectoral Implant-Based Reconstruction on Post-Mastectomy Radiation Dosimetry.Annals of surgical oncology · 2025Article
- Assessing shoulder muscle stretch reflexes following breast cancer treatment and postmastectomy breast reconstruction.Journal of neurophysiology · 2023Article
- Changes in pectoralis major stiffness and thickness following radiotherapy for breast cancer: A 12-month follow-up case series.Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology · 2023Article
- The impact of local therapies for breast cancer on shoulder muscle health and function.Critical reviews in oncology/hematology · 2022Review
- Article
- Near-infrared laparoscopy with indocyanine green for axillary sentinel lymph node biopsy in early breast cancer: preliminary experience of a single unit.Gland surgery · 2021Article
- Analysis of Radiation Dose to the Shoulder by Treatment Technique and Correlation With Patient Reported Outcomes in Patients Receiving Regional Nodal Irradiation.Frontiers in oncology · 2021Article
- The Influence of Functional Shoulder Biomechanics as a Mediator of Patient-Reported Outcomes following Mastectomy and Breast Reconstruction.Plastic and reconstructive surgery · 2021Article
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Breast-conserving surgery (BCS) and radiotherapy reduce breast cancer recurrence but can cause functional deficits in breast cancer survivors. A cross-sectional study quantified the long-term pathophysiological impact of these treatments on biomechanical measures of shoulder stiffness and ultrasound shear wave elastography measures of the shear elastic modulus of the pectoralis major (PM). Nine node-positive patients treated with radiotherapy to the breast and regional nodes after BCS and axillary lymph node dissection (Group 1) were compared to nine node-negative patients treated with radiotherapy to the breast alone after BCS and sentinel node biopsy (Group 2) and nine healthy age-matched controls. The mean follow-up for Group 1 and Group 2 patients was 988 days and 754 days, respectively. Shoulder stiffness did not differ between the treatment groups and healthy controls (p = 0.23). The PM shear elastic modulus differed between groups (p = 0.002), with Group 1 patients exhibiting a stiffer PM than Group 2 patients (p < 0.001) and healthy controls (p = 0.027). The mean prescribed radiotherapy dose to the PM was significantly correlated with passive shear elastic modulus (p = 0.018). Breast cancer patients undergoing more extensive axillary surgery and nodal radiotherapy did not experience long-term functional deficits to shoulder integrity but did experience long-term mechanical changes of the PM.
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