ArticleScientific reports2019
Histopathology Feature Mining and Association with Hyperspectral Imaging for the Detection of Squamous Neoplasia.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 22 citations in OpenAlex.
- Medical hyperspectral imaging: an updated review of technology advancements and biomedical applications.Journal of biomedical optics · 2026Pooled it
- Hyperspectral imaging in oral oncology: a scoping review.Frontiers in oral health · 2026Pooled it
- Gene Expression Alterations Associated With Resveratrol-Induced Antiproliferative Effects and S-Phase Cell Cycle Arrest in Osteosarcoma Cancer Cells.Journal of cellular and molecular medicine · 2026Article
- Enhancing Oral Health Diagnostics With Hyperspectral Imaging and Computer Vision: Clinical Dataset Study.JMIR medical informatics · 2025Article
- Diffuse reflectance spectroscopy for optical characterizations of orthotopic head and neck cancer modelsBiomedical optics express · 2024Article
- Evaluation of Preprocessing Methods on Independent Medical Hyperspectral Databases to Improve Analysis.Sensors (Basel, Switzerland) · 2022Article
- Comparison between image texture and polarization features in histopathology.Biomedical optics express · 2021Article
- Application of Microspectral Imaging in Motor and Sensory Nerve Classification.Journal of healthcare engineering · 2021Article
- Hyperspectral imaging and characterization of allergic contact dermatitis in the short-wave infrared.Journal of biophotonics · 2020Article
- Article
- An automatic whole-slide hyperspectral imaging microscope.Proceedings of SPIE--the International Society for Optical EngineeringArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
Hyperspectral imaging (HSI) is a noninvasive optical modality that holds promise for early detection of tongue lesions. Spectral signatures generated by HSI contain important diagnostic information that can be used to predict the disease status of the examined biological tissue. However, the underlying pathophysiology for the spectral difference between normal and neoplastic tissue is not well understood. Here, we propose to leverage digital pathology and predictive modeling to select the most discriminative features from digitized histological images to differentiate tongue neoplasia from normal tissue, and then correlate these discriminative pathological features with corresponding spectral signatures of the neoplasia. We demonstrated the association between the histological features quantifying the architectural features of neoplasia on a microscopic scale, with the spectral signature of the corresponding tissue measured by HSI on a macroscopic level. This study may provide insight into the pathophysiology underlying the hyperspectral dataset.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.