ArticleTranslational psychiatry2019
Sleep EEG slow-wave activity in medicated and unmedicated children and adolescents with attention-deficit/hyperactivity disorder.
Article in Translational psychiatry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 40 citations in OpenAlex.
- Article
- Tracing infant sleep neurophysiology longitudinally from 3 to 6 months: EEG insights into brain development.Npj biological timing and sleep · 2026Article
- Human brain imaging with high-density electroencephalography: Techniques and applications.The Journal of physiology · 2026Review
- Recent Evidence of Non-Rapid Eye Movement Sleep Oscillation Abnormalities in Psychiatric Disorders.Current psychiatry reports · 2025Review
- Wake EEG oscillation dynamics reflect both sleep pressure and brain maturation across childhood and adolescence.bioRxiv : the preprint server for biology · 2025Article
- Article
- NREM Slow-Wave Activity in Adolescents Is Differentially Associated With ADHD Levels and Normalized by Pharmacological Treatment.The international journal of neuropsychopharmacology · 2024Article
- Evidence of how the maturing sleeping brain contributes to the sleepy brain of adolescents.Sleep · 2024Article
- Lack of association between behavioral development and simplified topographical markers of the sleep EEG in infancy.Neurobiology of sleep and circadian rhythms · 2023Article
- The sleep and wake electroencephalogram over the lifespan.Neurobiology of aging · 2023Article
- Owner-rated hyperactivity/impulsivity is associated with sleep efficiency in family dogs: a non-invasive EEG study.Scientific reports · 2023Article
- A failure of sleep-dependent consolidation of visuoperceptual procedural learning in young adults with ADHD.Translational psychiatry · 2022Article
- Article
- Article
- Sleep Power Topography in Children with Attention Deficit Hyperactivity Disorder (ADHD).Children (Basel, Switzerland) · 2022Article
- Evidence of a maturational disruption in non-rapid eye movement sleep slow wave activity in youth with attention-deficit/hyperactivity, learning and internalizing disorders.Sleep medicine · 2022Article
- Sleep Stage Classification Based on Multi-Centers: Comparison Between Different Ages, Mental Health Conditions and Acquisition Devices.Nature and science of sleep · 2022Article
- What Is the Link Between Attention-Deficit/Hyperactivity Disorder and Sleep Disturbance? A Multimodal Examination of Longitudinal Relationships and Brain Structure Using Large-Scale Population-Based Cohorts.Biological psychiatry · 2020Article
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Authors and funding
12 authors at 3 institutions in 2 countries.
Funding
Abstract
Slow waves (1-4.5 Hz) are the most characteristic oscillations of deep non-rapid eye movement sleep. The EEG power in this frequency range (slow-wave activity, SWA) parallels changes in cortical connectivity (i.e., synaptic density) during development. In patients with attention-deficit/hyperactivity disorder (ADHD), prefrontal cortical development was shown to be delayed and global gray matter volumes to be smaller compared to healthy controls. Using data of all-night recordings assessed with high-density sleep EEG of 50 children and adolescents with ADHD (mean age: 12.2 years, range: 8-16 years, 13 female) and 86 age- and sex-matched healthy controls (mean age: 12.2 years, range: 8-16 years, 23 female), we investigated if ADHD patients differ in the level of SWA. Furthermore, we examined the effect of stimulant medication. ADHD patients showed a reduction in SWA across the whole brain (-20.5%) compared to healthy controls. A subgroup analysis revealed that this decrease was not significant in patients who were taking stimulant medication on a regular basis at the time of their participation in the study. Assuming that SWA directly reflects synaptic density, the present findings are in line with previous data of neuroimaging studies showing smaller gray matter volumes in ADHD patients and its normalization with stimulant medication.
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