ArticleAJNR. American journal of neuroradiology2019
Comparing Morphology and Hemodynamics of Stable-versus-Growing and Grown Intracranial Aneurysms.
Article in AJNR. American journal of neuroradiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Morphological Stability of Intracranial Aneurysms and the Contour Neurovascular System: A Longitudinal Analysis.Cardiovascular engineering and technology · 2026Article
- Risk factor analysis of growing unruptured intracranial aneurysms: A single center cohort study.Brain & spine · 2026Article
- Confocal Raman microspectroscopy imaging reveals structural protein reorganization in human intracranial aneurysm tissue.Scientific reports · 2025Article
- Computational Fluid Dynamics Approaches for Analyzing Rupture and Growth of Intracranial Aneurysms: A Systematic Review.Biomedicines · 2025Review
- Intracranial Aneurysm Wall Phenotypes: Clinical, Morphological, and Hemodynamic Influences.Stroke (Hoboken, N.J.) · 2025Article
- Predictive modeling and machine learning show poor performance of clinical, morphological, and hemodynamic parameters for small intracranial aneurysm rupture.Scientific reports · 2025Article
- Competing pathways of intracranial aneurysm growth: linking regional growth distribution and hemodynamics.Journal of neurosurgery · 2025Article
- Fluid structure Interaction analysis for rupture risk assessment in patients with middle cerebral artery aneurysms.Scientific reports · 2025Article
- Rupture risk assessment for AComA aneurysms with morphological, hemodynamic and structural mechanical analysis.PloS one · 2025Article
- Risk factors and predictive indicators of rupture in cerebral aneurysms.Frontiers in physiology · 2024Review
- Nomograms for assessing the rupture risk of anterior choroid artery aneurysms based on clinical, morphological, and hemodynamic features.Frontiers in neurology · 2024Article
- A Review of Artificial Intelligence in the Rupture Risk Assessment of Intracranial Aneurysms: Applications and Challenges.Brain sciences · 2023Review
- Image-derived Metrics Quantifying Hemodynamic Instability Predicted Growth of Unruptured Intracranial Aneurysms.Stroke (Hoboken, N.J.) · 2023Article
- Relationship between 3D Morphologic Change and 2D and 3D Growth of Unruptured Intracranial Aneurysms.AJNR. American journal of neuroradiology · 2022Article
- Luminal enhancement in intracranial aneurysms: fact or feature?-A quantitative multimodal flow analysis.International journal of computer assisted radiology and surgery · 2021Article
- Reliability and Agreement of 2D and 3D Measurements on MRAs for Growth Assessment of Unruptured Intracranial Aneurysms.AJNR. American journal of neuroradiology · 2021Article
- Multimodal validation of focal enhancement in intracranial aneurysms as a surrogate marker for aneurysm instability.Neuroradiology · 2020Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeAneurysm growth has been related to higher rupture risk. A better understanding of the characteristics related to growth may assist in the treatment decisions of unruptured intracranial aneurysms. This study aimed to identify morphologic and hemodynamic characteristics associated with aneurysm growth and to determine whether these characteristics deviate further from those of stable aneurysms after growth. MATERIALS AND
methodsWe included 81 stable and 56 growing aneurysms. 3D vascular models were segmented on CTA, MRA, or 3D rotational angiographic images. With these models, we performed computational fluid dynamics simulations. Morphologic (size, size ratios, and shape) and hemodynamic (inflow, vorticity, shear stress, oscillatory shear index, flow instability) characteristics were automatically calculated. We compared the characteristics between aneurysms that were stable and those that had grown at baseline and final imaging. The significance level after Bonferroni correction was
resultsAt baseline, no significant differences between aneurysms that were stable and those that had grown were detected (
conclusionsMorphologic and hemodynamic characteristics at baseline were not associated with aneurysm growth in our population. After growth, almost all indices increase toward values associated with higher rupture risks. Therefore, we stress the importance of longitudinal imaging and repeat risk assessment in unruptured aneurysms.
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