Evidence map›Paper›PMID 31779866›Full record

ArticleIndian heart journal

Evaluation of intracoronary blood from obstructive vessel in patients of ST-elevation myocardial infarction undergoing PPCI.

Suraj Kumar, Gurpreet S Wander, Bhupinder Singh, Maninder Kansal, Bishav Mohan, Naved Aslam, Shibba T Chabbra, Abhishek Goyal, Sumit Kumar

Open access · goldAbstract read
In one paragraph

Article in Indian heart journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Suraj KumarDepartment of Cardiology, Government Medical College and Hospital, Chandigarh, India. Electronic address: drskarora87@gmail.com.
Gurpreet S WanderDepartment of Cardiology, Dayanand Medical College and Hospital, Ludhiana, India.
Bhupinder SinghDepartment of Cardiology, Dayanand Medical College and Hospital, Ludhiana, India.
Maninder KansalDepartment of Medicine, Dayanand Medical College and Hospital, Ludhiana, India.
Bishav MohanDepartment of Cardiology, Dayanand Medical College and Hospital, Ludhiana, India.
Naved AslamDepartment of Cardiology, Dayanand Medical College and Hospital, Ludhiana, India.
Shibba T ChabbraDepartment of Cardiology, Dayanand Medical College and Hospital, Ludhiana, India.
Abhishek GoyalDepartment of Cardiology, Dayanand Medical College and Hospital, Ludhiana, India.
Sumit KumarDepartment of Medicine, Guru Gobind Singh Medical College and Hospital, Faridkot, India.
Dayanand Medical College & Hospital · INGovernment Medical College and Hospital · INGuru Gobind Singh Medical College and Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveInformation available on acid-base imbalance in ST-elevation myocardial infarction (STEMI) submitted to primary percutaneous intervention is limited and no data were present on intracoronary blood analysis, extracted from obstructed artery.

methodsThis was a prospective study conducted over 12 months in which STEMI patients presenting in emergency and undergoing primary percutaneous coronary intervention were included. Blood gas analysis of intracoronary arterial blood from obstructed vessel and peripheral arterial blood was performed. Patients in whom adequate intracoronary sample could not be obtained were excluded. Intracoronary and peripheral arterial blood gas measurements were correlated and relationship of intracoronary parameters were compared with clinical parameters, investigational markers and short-term outcome.

resultsThe mean age of study population was 54.8 years and average symptom onset to door time was 162 min. On comparing intracoronary blood with peripheral blood arterial obtained, pH (95% confidence interval [CI] -0.01 to 0.02;p = 0.44), lactate (95% CI 0.03-0.1;p = 0.28), bicarbonate (95% CI 0.6-1.5;p = 0.64), pCO

conclusionThe evaluation of intracoronary blood provides no additional information regarding the prognosis and short-term (30-day) outcome of the patients when compared with peripheral blood. However, there was a significant intracoronary hyperlactatemia in patients presenting late after symptom onset. SBP was also significantly less in patients with high intracoronary lactate, which signifies that predominant cause of hyperlactatemia was systemic hypoperfusion rather than local increase in lactate levels.

Indexed as

Blood Gas AnalysisPercutaneous Coronary InterventionBiomarkersFemaleHumansIndiaMaleMiddle AgedProspective StudiesST Elevation Myocardial InfarctionBiomarkersAcidosisIntracoronary bloodLactatePPCIST-elevation MI

Identifiers

PMID31779866
PMCPMC6890943
OpenAlexW2899621792

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.