Evidence map›Paper›PMID 31779793›Full record

ArticleJournal of the American College of Cardiology2019

Improvement in Pediatric Cardiac Surgical Outcomes Through Interhospital Collaboration.

Michael Gaies, Sara K Pasquali, Mousumi Banerjee, Justin B Dimick, John D Birkmeyer, Wenying Zhang, Jeffrey A Alten, Nikhil Chanani, David S Cooper, John M Costello and 9 more

Abstract readMulticenter Study
In one paragraph

Article in Journal of the American College of Cardiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Risk Models for Monitoring Postoperative Complication Rates After Paediatric Cardiac Surgery.European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery · 2025
    Article
  7. Observational
  8. Article
  9. Review
  10. Article
  11. Article
  12. Observational
  13. Article
  14. Article
  15. 2023 HRS/EHRA/APHRS/LAHRS Expert Consensus Statement on Practical Management of the Remote Device Clinic.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023
    Article
  16. Fetal Brain Development in Congenital Heart Disease.The Canadian journal of cardiology · 2023
    Review
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

19 authors.

Michael GaiesDepartment of Pediatrics, University of Michigan Medical School, Ann Arbor, Michigan. Electronic address: mgaies@med.umich.edu.
Sara K PasqualiDepartment of Pediatrics, University of Michigan Medical School, Ann Arbor, Michigan.
Mousumi BanerjeeDepartment of Biostatistics, University of Michigan School of Public Health, Ann Arbor, Michigan.
Justin B DimickDepartment of Surgery, University of Michigan Medical School, Ann Arbor, Michigan.
John D BirkmeyerSound Physicians, Tacoma, Washington.
Wenying ZhangCenter for Health Outcomes and Policy, University of Michigan, Ann Arbor, Michigan.
Jeffrey A AltenDepartment of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio.
Nikhil ChananiDepartment of Pediatrics, Emory University School of Medicine, Atlanta, Georgia.
David S CooperDepartment of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio.
John M CostelloDepartment of Pediatrics, Medical University of South Carolina, Charleston, South Carolina.
J William GaynorDepartment of Surgery, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania.
Nancy GhanayemDepartment of Pediatrics, Baylor College of Medicine, Houston, Texas.
Jeffrey P JacobsThe Society of Thoracic Surgeons, Chicago, Illinois.
John E MayerDepartment of Cardiac Surgery, Harvard Medical School, Boston, Massachusetts.
Richard G OhyeDepartment of Cardiac Surgery, University of Michigan Medical School, Ann Arbor, Michigan.
Mark A ScheurerDepartment of Pediatrics, Medical University of South Carolina, Charleston, South Carolina.
Steven M SchwartzDepartments of Pediatrics and Critical Care Medicine, University of Toronto, Toronto, Ontario, Canada.
Sarah TabbuttDepartment of Pediatrics, University of California, San Francisco School of Medicine, San Francisco, California.
John R CharpieDepartment of Pediatrics, University of Michigan Medical School, Ann Arbor, Michigan.

Funding

Michigan Institute for Clinical and Health Research (MICHR)UL1TR002240 · NCATS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LUMENG, JULIE C, MASHOUR, GEORGE ALEXANDER · 2017 to 2022
$54.9M
Understanding Quality and Costs in Congenital Heart SurgeryR01HL122261 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI PASQUALI, SARA · 2014 to 2019
$2.8M
Explaining Variation in Mortality after Pediatric Cardiac SurgeryK08HL116639 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI GAIES, MICHAEL · 2014 to 2018
$767k
NCATS NIH HHS UL1 TR002240NHLBI NIH HHS K08 HL116639NHLBI NIH HHS R01 HL122261
6 · The paper itself

Abstract

backgroundPatients undergoing complex pediatric cardiac surgery remain at considerable risk of mortality and morbidity, and variation in outcomes exists across hospitals. The Pediatric Cardiac Critical Care Consortium (PC4) was formed to improve the quality of care for these patients through transparent data sharing and collaborative learning between participants.

objectivesThe purpose of this study was to determine whether outcomes improved over time within PC4.

methodsThe study analyzed 19,600 hospitalizations (18 hospitals) in the PC4 clinical registry that included cardiovascular surgery from August 2014 to June 2018. The primary exposure was 2 years of PC4 participation; this provided adequate time for hospitals to accrue data and engage in collaborative learning. Aggregate case mix-adjusted outcomes were compared between the first 2 years of participation (baseline) and all months post-exposure. We also evaluated outcomes from the same era in a cohort of similar, non-PC4 hospitals.

resultsDuring the baseline period, there was no evidence of improvement. We observed significant improvement in the post-exposure period versus baseline for post-operative intensive care unit mortality (2.1% vs. 2.7%; 22% relative reduction [RR]; p = 0.001), in-hospital mortality (2.5% vs. 3.3%; 24% RR; p = 0.001), major complications (10.1% vs. 11.5%; 12% RR; p < 0.001), intensive care unit length of stay (7.3 days vs. 7.7 days; 5% RR; p < 0.001), and duration of ventilation (61.3 h vs. 70.6 h; 13% RR; p = 0.01). Non-PC4 hospitals showed no significant improvement in mortality, complications, or hospital length of stay.

conclusionsThis analysis demonstrates improving cardiac surgical outcomes at children's hospitals participating in PC4. This change appears unrelated to secular improvement trends, and likely reflects PC4's commitment to transparency and collaboration.

Indexed as

Cooperative BehaviorCardiac Surgical ProceduresChild, PreschoolCritical CareFemaleHeart Defects, CongenitalHospital MortalityHumansInfantInfant, NewbornIntensive Care UnitsMaleMorbidityPostoperative ComplicationsQuality ImprovementRegistriescardiac surgerycollaborative learningcongenitaloutcomespediatricquality

Identifiers

PMID31779793
PMCPMC6981276

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.