ArticleJournal of orthopaedic surgery and research2019
Functional outcomes after total joint arthroplasty are related to the severity of Parkinson's disease: a mid-term follow-up.
Article in Journal of orthopaedic surgery and research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 21 citations in OpenAlex.
- Parkinson's Disease Patients Face Higher 90-Day Readmission, Reoperation, and Infection Risk Following Total Knee Arthroplasty.Arthroplasty today · 2026Article
- Unicompartmental knee arthroplasty in patients with Parkinson's disease.Archives of orthopaedic and trauma surgery · 2026Article
- Survival of total knee arthroplasty in patients with Parkinson's disease: a registry study.International orthopaedics · 2025Article
- Neurologic and psychiatric disorders as risk factors following hip arthroplasty: results from the German arthroplasty registry.International orthopaedics · 2025Article
- Levodopa-Carbidopa Intestinal Gel Injection for Patient with Severe Parkinson's Disease Followed by Total Hip Arthroplasty: A Case Report and Literature Review.Orthopaedic surgery · 2023Review
- The effect of Parkinson's disease on total knee arthroplasty: a systematic review and meta-analysis.Knee surgery & related research · 2023Article
- Total Hip Arthroplasty in Patients With Neurological Conditions: A Systematic Review.Arthroplasty today · 2023Article
- The impact of Parkinson's disease on results of primary total knee arthroplasty.EFORT open reviews · 2022Review
- Musculoskeletal pain in Parkinson's disease: a narrative review.Neurodegenerative disease management · 2021Review
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
backgroundPerforming total joint arthroplasty (TJA) in Parkinson's disease (PD) patients may encounter a higher complication rate or worse functional outcomes compared with common patients. The relationship between PD and clinical outcomes after TJA is not fully understood.
methodsRetrospectively, we used manual charts to investigate the clinical outcomes in 41 patients including 24 total hip arthroplasty (THA) patients (28 hips) and 18 total knee arthroplasty (TKA) patients (22 knees) with a diagnosis of PD from 2009 to 2016. The stage of PD was confirmed by Hoehn and Yahr scale. Prosthesis survivorship was estimated with revision for any reason as the endpoint.
resultAll the clinical outcomes improved significantly (p < 0.05). Subgroup analysis revealed worse functional outcomes in mid- or end-stage PD patients. Sixteen short-term mild to moderate complications were noted. Two revisions were conducted for hip periprosthetic osteolysis and postoperative knee pain. The prosthesis survivorship at 60 months for TJA, total hip arthroplasty (THA), or total knee arthroplasty (TKA) was 91.6%, 94.1%, and 87.5%, respectively.
conclusionPatients with PD who underwent TJA would result in excellent pain relief and gain of function. However, patients at late-stage PD may suffer from functional loss. The effectiveness of TJA in patients with severe PD remains a concern. Physician should help delay the progression of PD which may optimize and stabilize the functional outcomes of TJA.
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