ArticleConnective tissue research2021
Contribution of extracellular matrix components to the stiffness of skeletal muscle contractures in patients with cerebral palsy.
Registry-linked trialOpen access · greenAbstract read
In one paragraph
Article in Connective tissue research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04437056 (Outcome Measurements After Cognitive Nerve Transfers to Spastic Muscles in Stroke Patients), which is not on this map. Cited by 34 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 7% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Outcome Measurements After Cognitive Nerve Transfers to Spastic Muscles in Stroke Patients
Who cites it
34 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.
- Alterations in intramuscular connective tissue in hypertonic muscle: a scoping review.Frontiers in physiology · 2025Pooled it
- Depot-specific differences in visceral and subcutaneous adipose tissue from patients with obesity.Adipocyte · 2026Article
- Untargeted Metabolomic Profiling Identifies Breed-Specific Metabolomic Signatures in the Longissimus Dorsi Meat of Beichuan White Goats and Tianfu Goats.Metabolites · 2026Article
- Observational
- Single cell analysis of muscle contracture in cerebral palsy reveals profibrotic and antimyogenic stem cell populations with altered cell-cell interactions.American journal of physiology. Cell physiology · 2026Article
- Macrophages, muscle stem cells, and repair; immunohistochemical characteristics in muscle growth impairments in children with cerebral palsy.American journal of physiology. Cell physiology · 2026Article
- Microscopic and molecular aspects of skeletal muscle alterations in cerebral palsy.Developmental medicine and child neurology · 2026Review
- Comprehensive lipoprotein and glycoprotein characterization in rheumatoid arthritis plasma and association with clinical markers.Frontiers in molecular biosciences · 2025Article
- Muscle satellite cells and fibro-adipogenic progenitors from muscle contractures of children with cerebral palsy have impaired regenerative capacity.Developmental medicine and child neurology · 2025Article
- Collagen architecture and biomechanics of gracilis and adductor longus muscles from children with cerebral palsy.The Journal of physiology · 2024Article
- Targeted multifidus muscle activation reduces fibrosis of multifidus muscle following intervertebral disc injury.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2024Article
- Neuromuscular contributions to disability in children with cerebral palsy and the impact of dynamic stretching orthoses and therapeutic exercise interventions: a narrative review.Translational pediatrics · 2024Review
- Focal Traumatic Brain Injury Impairs the Integrity of the Basement Membrane of Hindlimb Muscle Fibers Revealed by Extracellular Matrix Immunoreactivity.Life (Basel, Switzerland) · 2024Article
- Thrown for a loop: fibro-adipogenic progenitors in skeletal muscle fibrosis.American journal of physiology. Cell physiology · 2023Review
- Alignment, cross linking, and beyond: a collagen architect's guide to the skeletal muscle extracellular matrix.American journal of physiology. Cell physiology · 2023Review
- Article
- The extracellular matrix of dystrophic mouse diaphragm accounts for the majority of its passive stiffness and is resistant to collagenase digestion.Matrix biology plus · 2023Article
- Structure-Function relationships in the skeletal muscle extracellular matrix.Journal of biomechanics · 2023Review
- Tissue engineering modalities in skeletal muscles: focus on angiogenesis and immunomodulation properties.Stem cell research & therapy · 2023Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 1 country.
Lucas R SmithDepartments of Neurobiology, Physiology, and Behavior and Physical Medicine and Rehabilitation, University of California, Davis, CA, USA.ORCID 0000-0002-7610-4231
Rajeswari PichikaShirley Ryan AbilityLab and Department of Physical Medicine and Rehabilitation, Northwestern University, Chicago, IL, USA.
Rachel C MezaDepartment of Orthopaedic Surgery, University of California San Diego, La Jolla, CA, USA.
Allison R GilliesDepartment of Orthopaedic Surgery, University of California San Diego, La Jolla, CA, USA.ORCID 0000-0002-5573-6547
Marwan N BalikiShirley Ryan AbilityLab and Department of Physical Medicine and Rehabilitation, Northwestern University, Chicago, IL, USA.
Henry G ChambersDepartment of Orthopaedics, Rady Children's Hospital, San Diego, CA, USA.
Richard L LieberShirley Ryan AbilityLab and Department of Physical Medicine and Rehabilitation, Northwestern University, Chicago, IL, USA.ORCID 0000-0002-7203-4520
Northwestern University · USUniversity of California San Diego · USRady Children's Hospital-San Diego · USUniversity of California, Davis · US
Funding
National Center for Muscle Rehabilitation ResearchR24HD050837 · NICHD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI LIEBER, RICHARD L., WARD, SAMUEL RICHARD · 2005 to 2014
$7.2MSan Diego Skeletal Muscle Research CenterP30AR061303 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI LIEBER, RICHARD L. · 2011 to 2015
$3.3MMuscle Biological and Biomechanical Response in Cerebral PalsyR01AR057393 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI LIEBER, RICHARD L. · 2010 to 2014
$1.7MThe role of collagen organization in determination of fibrotic muscle function and regenerationR00AR067867 · NIAMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI SMITH, LUCAS R · 2018 to 2020
$741kIntraoperative Optimization and Validation of Musculoskeletal ReconstructionI01RX002462 · VA · EDWARD HINES JR VA HOSPITAL · PI LIEBER, RICHARD L. · 2018 to 2025
–RR&D Senior Research Career Scientist Award ApplicationIK6RX003351 · VA · EDWARD HINES JR VA HOSPITAL · PI LIEBER, RICHARD L. · 2020 to 2025
–NIAMS NIH HHS P30 AR061303NIAMS NIH HHS R00 AR067867NIAMS NIH HHS R01 AR057393NICHD NIH HHS R24 HD050837RRD VA I01 RX002462RRD VA IK6 RX003351
Abstract
PubMed holds no abstract for this paper.
Indexed as
Cerebral PalsyContractureBiglycanChildCollagenExtracellular MatrixHumansMuscle, SkeletalBiglycanCollagenCerebral palsycollagenextracellular matrixmusclestiffness
Identifiers
What OpenQuestion holds
Textmetadata
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Read underepoch 390
Registered trials
NCT04437056ClinicalTrials.gov
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.