Evidence map›Paper›PMID 31779280›Full record

ArticleCells2019

Expression of miRNAs from the Imprinted

Laetitia Barrault, Jacqueline Gide, Tingting Qing, Lea Lesueur, Jorg Tost, Jerome Alexandre Denis, Michel Cailleret, Laetitia Aubry, Marc Peschanski, Cécile Martinat and 1 more

Open access · goldAbstract read
In one paragraph

Article in Cells, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Laetitia BarraultCECS/AFM, I-STEM, 91100 Corbeil-Essonnes, France.
Jacqueline GideCECS/AFM, I-STEM, 91100 Corbeil-Essonnes, France.
Tingting QingCECS/AFM, I-STEM, 91100 Corbeil-Essonnes, France.
Lea LesueurINSERM/ UEVE UMR 861, Paris Saclay Univ I-STEM, 91100 Corbeil-Essonnes, France.
Jorg TostLEE/ CNRGH/ CEA-IBFJ 2, 91000 Evry, France.ORCID 0000-0002-2683-0817
Jerome Alexandre DenisINSERM/ UEVE UMR 861, Paris Saclay Univ I-STEM, 91100 Corbeil-Essonnes, France.ORCID 0000-0002-1617-4617
Michel CailleretINSERM/ UEVE UMR 861, Paris Saclay Univ I-STEM, 91100 Corbeil-Essonnes, France.ORCID 0000-0002-8937-9875
Laetitia AubryINSERM/ UEVE UMR 861, Paris Saclay Univ I-STEM, 91100 Corbeil-Essonnes, France.
Marc PeschanskiCECS/AFM, I-STEM, 91100 Corbeil-Essonnes, France.
Cécile MartinatINSERM/ UEVE UMR 861, Paris Saclay Univ I-STEM, 91100 Corbeil-Essonnes, France.ORCID 0000-0002-5234-1064
Sandrine BaghdoyanINSERM/ UEVE UMR 861, Paris Saclay Univ I-STEM, 91100 Corbeil-Essonnes, France.
Inserm · FRInstitut des Cellules Souches pour le Traitement et l'Étude des Maladies Monogéniques · FRCommissariat à l'Énergie Atomique et aux Énergies Alternatives · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Substantial variations in differentiation properties have been reported among human pluripotent cell lines (hPSC), which could affect their utility and clinical safety. We characterized the variable osteogenic capacity observed between different human pluripotent stem cell lines. By focusing on the miRNA expression profile, we demonstrated that the osteogenic differentiation propensity of human pluripotent stem cell lines could be associated with the methylation status and the expression of miRNAs from the imprinted

Indexed as

BiomarkersCalcium-Binding ProteinsCell DifferentiationCell LineGene Expression Regulation, DevelopmentalGenomic ImprintingHumansImmunophenotypingIodide PeroxidaseMembrane ProteinsMicroRNAsOsteogenesisPluripotent Stem CellsQuantitative Trait LociRNA InterferenceBiomarkersCalcium-Binding ProteinsDLK1 protein, humanIodide Peroxidaseiodothyronine deiodinase type IIIMembrane ProteinsMicroRNAsACVR2Bhuman pluripotent stem cellsimprintingmicroRNAosteogenic differentiationvariability

Identifiers

PMID31779280
PMCPMC6953034
OpenAlexW2989796815

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.