Evidence map›Paper›PMID 31779271›Full record

ArticleCells2019

Synovial-Fluid miRNA Signature for Diagnosis of Juvenile Idiopathic Arthritis.

Nadége Nziza, Eric Jeziorski, Marion Delpont, Maïlys Cren, Hugues Chevassus, Aurélia Carbasse, Perrine Mahe, Hamouda Abassi, Pauline Joly-Monrigal, Eric Schordan and 4 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Cells, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02505828 (ARTEMIS Synovial Markers in Arthritis Childhood), which is not on this map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02505828 nacompletednot on this map

ARTEMIS Synovial Markers in Arthritis Childhood

TypeinterventionalSponsorUniversity Hospital, MontpellierRan2015 to 2018Enrolled30ConditionsSeptic Arthritis, Juvenile Idiopathic ArthritisArmsArticular punction, salivary samples, blood sample
3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Nadége NzizaIRMB, INSERM, Univ Montpellier, F-34000 Montpellier, France.
Eric JeziorskiPediatric Department, CHU Montpellier, Univ Montpellier, F-34000 Montpellier, France.
Marion DelpontPediatric Orthopedic Surgery Unit, CHU Montpellier, Univ Montpellier, F-34000 Montpellier, France.
Maïlys CrenIRMB, INSERM, Univ Montpellier, F-34000 Montpellier, France.
Hugues ChevassusCentre d'Investigation Clinique, CHU Montpellier, F-34000 Montpellier, France.
Aurélia CarbassePediatric Department, CHU Montpellier, Univ Montpellier, F-34000 Montpellier, France.
Perrine MahePediatric Department, CHU Montpellier, Univ Montpellier, F-34000 Montpellier, France.
Hamouda AbassiPediatric Department, CHU Montpellier, Univ Montpellier, F-34000 Montpellier, France.
Pauline Joly-MonrigalPediatric Orthopedic Surgery Unit, CHU Montpellier, Univ Montpellier, F-34000 Montpellier, France.
Eric SchordanFIRALIS SA, F- 68330 Huningue, France.
Alain MangéIRCM, INSERM, Univ Montpellier, ICM, F-34000 Montpellier, France.
Christian JorgensenIRMB, INSERM, Univ Montpellier, F-34000 Montpellier, France.
Florence ApparaillyIRMB, INSERM, Univ Montpellier, F-34000 Montpellier, France.
Isabelle Duroux-RichardIRMB, INSERM, Univ Montpellier, F-34000 Montpellier, France.
Inserm · FRUniversité de Montpellier · FRFiralis (France) · FR

Funding

RENAL PATHOGENICITY OF ANTIDNA ANTIBODIESK08AR002015 · NIAMS · YESHIVA UNIVERSITY · PI PUTTERMAN, CHAIM · 1997 to 2001
$252k
6 · The paper itself

Abstract

Juvenile idiopathic arthritis (JIA) is the most common chronic inflammatory rheumatism in childhood; microRNAs (miRNAs) have been proposed as diagnostic biomarkers. Although joints are the primary targets for JIA, a synovial fluid-based miRNA signature has never been studied. We aim to identify miRNA biomarkers in JIA by comparing synovial fluid and serum samples from children with JIA and

Indexed as

Circulating MicroRNAArthritis, JuvenileBiomarkersComputational BiologyFemaleGene Expression ProfilingGene Expression RegulationHumansLiquid BiopsyMaleMicroRNAsPrognosisSignal TransductionSynovial FluidBiomarkersCirculating MicroRNAMicroRNAsbiomarkerjuvenile arthritismiRNAsynovial fluid

Identifiers

PMID31779271
PMCPMC6952798
OpenAlexW2991019908

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.