Evidence map›Paper›PMID 31779172›Full record

ReviewCells2019

Fibronectin and Its Role in Human Infective Diseases.

Pietro Speziale, Carla Renata Arciola, Giampiero Pietrocola

Open access · goldAbstract readReview
In one paragraph

Review in Cells, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
6.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 83 citations in OpenAlex.

  1. Biology · 2026
    Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Raman signatures ofFrontiers in microbiology · 2026
    Article
  9. Differential Binding of ΔFN3 Proteins ofInternational journal of molecular sciences · 2025
    Article
  10. Article
  11. Article
  12. Potential Inhibitors of Human-Marine drugs · 2025
    Article
  13. A Novel Interaction of Staphylococcal Protein A With Human Fibronectin and Its Implications in Host Cell Adhesion.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Article
  14. Protein dysregulation duringFrontiers in immunology · 2025
    Article
  15. Article
  16. Potential Targeting Mechanisms for Bone-Directed Therapies.International journal of molecular sciences · 2024
    Review
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Pietro SpezialeDepartment of Molecular Medicine, Section of Biochemistry, University of Pavia, Viale Taramelli 3/b, 27100 Pavia, Italy.
Carla Renata ArciolaLaboratorio di Patologia delle Infezioni Associate all'Impianto, IRCCS Istituto Ortopedico Rizzoli, via di Barbiano 1/10, 40136 Bologna, Italy.ORCID 0000-0003-0382-0066
Giampiero PietrocolaDepartment of Molecular Medicine, Section of Biochemistry, University of Pavia, Viale Taramelli 3/b, 27100 Pavia, Italy.ORCID 0000-0002-7069-8155
University of Pavia · ITIstituto Ortopedico Rizzoli · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fibronectin is a multidomain glycoprotein ubiquitously detected in extracellular fluids and matrices of a variety of animal and human tissues where it functions as a key link between matrices and cells. Fibronectin has also emerged as the target for a large number of microorganisms, particularly bacteria. There are clear indications that the binding of microorganism' receptors to fibronectin promotes attachment to and infection of host cells. Each bacterium may use different receptors which recognize specific fibronectin domains, mostly the

Indexed as

Disease SusceptibilityHost-Pathogen InteractionsAnimalsBacterial InfectionsBacterial ProteinsBiomarkersCarrier ProteinsCommunicable DiseasesExtracellular MatrixFibronectinsHumansProtein BindingVirulence FactorsBacterial ProteinsBiomarkersCarrier ProteinsFibronectinsVirulence Factorsadhesinbacteriaextracellular matrixfibronectinvaccinevirulence factor

Identifiers

PMID31779172
PMCPMC6952806
OpenAlexW2991534536

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.