Evidence map›Paper›PMID 31778311›Full record

ArticleThe British journal of radiology2020

Quantification of gas exchange-related upward motion of the liver during prolonged breathholding-potential reduction of motion artifacts in abdominal MRI.

Rachita Khot, Melissa McGettigan, James T Patrie, Sebastian Feuerlein

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in The British journal of radiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07135401 (Optimizing MRI Liver Imaging), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07135401 narecruitingnot on this mapstarted 2025, after this paper: background citation

Optimizing MRI Liver Imaging: Evaluating Breath-Holding Techniques and Oxygen Supplementation to Reduce Respiratory Motion Artifacts

TypeinterventionalSponsorUniversity of California, San FranciscoRan2025 to 2026Enrolled10ConditionsMRI, MRI Image EnhancementArmsBreath-hold conditions
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Defining short and prolonged breath-holds.The British journal of radiology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Rachita KhotDepartment of Radiology and Medical Imaging, University of Virginia, Charlottesville, VA, United States.
Melissa McGettiganH Lee Moffitt Cancer Center and Research Institute, Tampa, 33612, United States.
James T PatrieDepartment of Public Health Sciences, University of Virginia, Charlottesville, VA, United States.
Sebastian FeuerleinH Lee Moffitt Cancer Center and Research Institute, Tampa, 33612, United States.
Moffitt Cancer Center · USUniversity of Virginia · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo test the hypothesis that there is a measureable upward motion of the diaphragm during prolonged breath-holds that could have a detrimental effect on image quality in liver MRI and to identify factor that potentially influence the magnitude of this motion.

methods15 healthy volunteers underwent MRI examination using prolonged breath-holds in the maximum inspiratory position and a moderate inspiratory position. Coronal

resultsAll volunteers demonstrated a slow reduction of the total lung volume during prolonged breath-holding up to 123 ml. There was a measurable associated upward shift of the diaphragm, measuring up to 5.6 mm after 24 s. There was a positive correlation with female gender (

conclusionThere is a measureable reduction of lung volumes with consecutive upward shift of the diaphragm during prolonged breath-holding which likely contributes to motion artifacts in liver MRI. ADVANCES IN KNOWLEDGE: There is a measureable gas exchange-related reduction of lung volumes with consecutive upward shift of the diaphragm during prolonged breath-holding which likely contributes to motion artifacts in liver MRI. Correcting for this predictable upward shift has potential to improve image quality.The magnitude of this effect does not seem to be related to gender, BMI or total lung capacity if a moderate inspiratory position is used.

Indexed as

Breath HoldingLiverAbdomenAdultArtifactsDiaphragmFemaleHealthy VolunteersHumansInhalationLung Volume MeasurementsMagnetic Resonance ImagingMaleMiddle AgedMovementPulmonary Gas Exchange

Identifiers

PMID31778311
PMCPMC7055431
OpenAlexW2991287600

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.