Trial reportHuman brain mapping2020
Brain oscillatory activity as a biomarker of motor recovery in chronic stroke.
Trial report in Human brain mapping, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed.
- EEG-controlled functional electrical stimulation rehabilitation for chronic stroke: system design and clinical application.Frontiers of medicine · 2021Trial
- Brain oscillatory activity as a biomarker of motor recovery in chronic stroke.Human brain mapping · 2020Trial
- Signatures of Covert Neuron Loss in the Local Field Potential of Motor Cortex.Journal of the American Heart Association · 2026Article
- EEG-based predictors of motor recovery during immersive VR-BCI rehabilitation.Scientific reports · 2026Article
- Non-linear and spectral EEG dynamics as stage-specific biomarkers of neuropsychological recovery post-stroke.Frontiers in neuroscience · 2026Article
- Reconnecting Brain Networks After Stroke: A Scoping Review of Conventional, Neuromodulatory, and Feedback-Driven Rehabilitation Approaches.Brain sciences · 2025Review
- Uncovering attempted movements of the paralyzed upper limb after stroke through EEG and EMG.Journal of neuroengineering and rehabilitation · 2025Article
- Quantifying and evaluating motor imagery ability using EEG microstates in MI-BCI training.Experimental brain research · 2025Article
- Alterations of static and dynamic changes in intrinsic brain activity and its relation to behavioral outcomes in subcortical ischemic stroke after one-month intervention.Scientific reports · 2025Article
- Exploring neural activity changes during motor imagery-based brain-computer interface training with robotic hand for upper limb rehabilitation in ischemic stroke patients: a pilot study.Frontiers in human neuroscience · 2025Article
- Exploring the Relationship between Abnormal Communication Efficiency of Cerebral Cortex and Multiple Cognitive Functions in Mild Subcortical Stroke: A Resting-State fMRI Study.Brain sciences · 2024Article
- Hebbian plasticity induced by temporally coincident BCI enhances post-stroke motor recovery.Scientific reports · 2024Article
- Electrophysiological Correlates of Dentate Nucleus Deep Brain Stimulation for Poststroke Motor Recovery.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Exploring the Prospects of Transcranial Electrical Stimulation (tES) as a Therapeutic Intervention for Post-Stroke Motor Recovery: A Narrative Review.Brain sciences · 2024Review
- Case report: Movement-related neuroplasticity in a patient after spinal cord injury in response to task-oriented bimanual training.Frontiers in human neuroscience · 2024Article
- Lesion-specific cortical activation following sensory stimulation in patients with subacute stroke.Journal of neuroengineering and rehabilitation · 2023Article
- A review on EMG/EEG based control scheme of upper limb rehabilitation robots for stroke patients.Heliyon · 2023Review
- Challenges of neural interfaces for stroke motor rehabilitation.Frontiers in human neuroscience · 2023Article
- A garment that measures brain activity: proof of concept of an EEG sensor layer fully implemented with smart textiles.Frontiers in human neuroscience · 2023Article
- Immediate neural effects of acupuncture manipulation time for stroke with motor dysfunction: a fMRI pilot study.Frontiers in neuroscience · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In the present work, we investigated the relationship of oscillatory sensorimotor brain activity to motor recovery. The neurophysiological data of 30 chronic stroke patients with severe upper-limb paralysis are the basis of the observational study presented here. These patients underwent an intervention including movement training based on combined brain-machine interfaces and physiotherapy of several weeks recorded in a double-blinded randomized clinical trial. We analyzed the alpha oscillations over the motor cortex of 22 of these patients employing multilevel linear predictive modeling. We identified a significant correlation between the evolution of the alpha desynchronization during rehabilitative intervention and clinical improvement. Moreover, we observed that the initial alpha desynchronization conditions its modulation during intervention: Patients showing a strong alpha desynchronization at the beginning of the training improved if they increased their alpha desynchronization. Patients showing a small alpha desynchronization at initial training stages improved if they decreased it further on both hemispheres. In all patients, a progressive shift of desynchronization toward the ipsilesional hemisphere correlates significantly with clinical improvement regardless of lesion location. The results indicate that initial alpha desynchronization might be key for stratification of patients undergoing BMI interventions and that its interhemispheric balance plays an important role in motor recovery.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.