Evidence map›Paper›PMID 31778001›Full record

ReviewAnnals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc2020

Diagnostic and prognostic role of electrocardiogram in acute myocarditis: A comprehensive review.

Carmelo Buttà, Luca Zappia, Giulia Laterra, Marco Roberto

Abstract readReview
In one paragraph

Review in Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
70citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

70 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Clinical characteristics associated with sustained ventricular arrhythmia among acute myocarditis patients: a multicenter case-control study.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2026
    Article
  3. Article
  4. Post-viral myocarditis.Heart failure reviews · 2026
    Review
  5. Observational
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Observational
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  14. ECG challenge: inversion without infarction.European heart journal. Case reports · 2025
    Article
  15. Observational
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article

10 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Carmelo ButtàCardiology Unit, Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy.ORCID 0000-0001-9856-4004
Luca ZappiaCardiology Unit, Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy.
Giulia LaterraCardiology Unit, Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy.
Marco RobertoDepartment of Cardiology, Cardiocentro Ticino, Lugano, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAcute myocarditis represents a challenging diagnosis as there is no pathognomonic clinical presentation. In patients with myocarditis, electrocardiogram (ECG) can display a variety of non-specific abnormalities. Nevertheless, ECG is widely used as an initial screening tool for myocarditis.

methodsWe researched all possible ECG alterations during acute myocarditis evaluating prevalence, physiopathology, correlation with clinical presentation patterns, role in differential diagnosis, and prognostic yield.

resultsThe most common ECG abnormality in myocarditis is sinus tachycardia associated with nonspecific ST/T-wave changes. The presence of PR segment depression both in precordial and limb leads, a PR segment depression in leads with ST segment elevation, a PR segment elevation in aVR lead or a ST elevation with pericarditis pattern favor generally diagnosis of perimyocarditis rather than myocardial infarction. In patients with acute myocarditis, features associated with a poorer prognosis are: pathological Q wave, wide QRS complex, QRS/T angle ≥ 100°, prolonged QT interval, high-degree atrioventricular block and malignant ventricular tachyarrhythmia. On the contrary, ST elevation with a typical early repolarization pattern is associated with a better prognosis.

conclusionsECG alterations in acute myocarditis could be very useful in clinical practice for a patient-tailored approach in order to decide appropriate therapy, length of hospitalization, and frequency of followup.

Indexed as

Acute DiseaseElectrocardiographyHumansMyocarditisPrognosisatrial fibrillation/atrial arrhythmiascardiac anatomyelectrocardiographyMRIventricular tachycardia/fibrillation

Identifiers

PMID31778001
PMCPMC7958927

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.