Evidence map›Paper›PMID 31777644›Full record

ArticleInternational journal of physiology, pathophysiology and pharmacology2019

Nitric oxide represses the proliferation of Caco-2 cells by inducing S-G

Satoru Sakuma, Yukino Ikeda, Itsumi Inoue, Kanna Yamaguchi, Shohko Honkawa, Tetsuya Kohda, Saaya Minamino, Yohko Fujimoto

Abstract read
PubMed Full text at PMC
In one paragraph

Article in International journal of physiology, pathophysiology and pharmacology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Satoru SakumaDepartment of Physiological Chemistry, Osaka University of Pharmaceutical Sciences 4-20-1 Nasahara, Takatsuki 569-1094, Osaka, Japan.
Yukino IkedaDepartment of Physiological Chemistry, Osaka University of Pharmaceutical Sciences 4-20-1 Nasahara, Takatsuki 569-1094, Osaka, Japan.
Itsumi InoueDepartment of Physiological Chemistry, Osaka University of Pharmaceutical Sciences 4-20-1 Nasahara, Takatsuki 569-1094, Osaka, Japan.
Kanna YamaguchiDepartment of Physiological Chemistry, Osaka University of Pharmaceutical Sciences 4-20-1 Nasahara, Takatsuki 569-1094, Osaka, Japan.
Shohko HonkawaDepartment of Physiological Chemistry, Osaka University of Pharmaceutical Sciences 4-20-1 Nasahara, Takatsuki 569-1094, Osaka, Japan.
Tetsuya KohdaDepartment of Physiological Chemistry, Osaka University of Pharmaceutical Sciences 4-20-1 Nasahara, Takatsuki 569-1094, Osaka, Japan.
Saaya MinaminoDepartment of Physiological Chemistry, Osaka University of Pharmaceutical Sciences 4-20-1 Nasahara, Takatsuki 569-1094, Osaka, Japan.
Yohko FujimotoDepartment of Physiological Chemistry, Osaka University of Pharmaceutical Sciences 4-20-1 Nasahara, Takatsuki 569-1094, Osaka, Japan.
Osaka University of Pharmaceutical Sciences · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is conflicting data regarding the ability of nitric oxide (NO) to promote or inhibit colorectal cancer cell proliferation. Furthermore, NO reacts rapidly with endogenous superoxide at a diffusion-controlled rate to give peroxynitrite (ONOO

Indexed as

colon cancer proliferationNitric oxideNOR5peroxynitritereactive nitrogen speciesSIN-1

Identifiers

PMID31777644
PMCPMC6872484
OpenAlexW2995679970

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.