ArticlePakistan journal of medical sciences
Undiagnosed Hemoglobinopathies: A potential threat to the premarital screening program.
Article in Pakistan journal of medical sciences. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 23 citations in OpenAlex.
- Characterisation of RHD and RHCE variations in blood donors from Jazan Province, Southwestern Saudi Arabia.Transfusion medicine (Oxford, England) · 2026Article
- Evaluation of β-thalassemias in the premarital hemoglobinopathy screening program: A retrospective study.Pakistan journal of medical sciences · 2025Article
- Family Planning practices among the parents of beta thalassemia major patients in Makran division, Balochistan: A cross-sectional study.Pakistan journal of medical sciences · 2025Article
- Assessing Nutritional Anemia Among University Students in Jazan, Saudi Arabia: A Public Health Perspective.Journal of blood medicine · 2024Article
- Red Cell Alloimmunisation Among Sickle Cell Disease and Thalassemia Patients Following Rh- and K-Matched Red Cell Transfusion in Southwestern Saudi Arabia: A Multicenter Study.International journal of general medicine · 2024Article
- Comparative Analysis of Red Blood Cells, White Blood Cells, Platelet Count, and Indices in Type 2 Diabetes Mellitus Patients and Normal Controls: Association and Clinical Implications.Diabetes, metabolic syndrome and obesity : targets and therapy · 2023Article
- Red Cell Alloimmunization and Autoimmunization Among Sickle Cell Disease and Thalassemia Patients in Jazan Province, Saudi Arabia.International journal of general medicine · 2022Article
- Five novel globin gene mutations identified in five Chinese families by next-generation sequencing.Molecular genetics & genomic medicine · 2021Article
- Assessment of Factors Associated with the Effectiveness of Premarital Screening for Hemoglobinopathies in the South of Saudi Arabia.International journal of general medicine · 2021Article
- Prevalence of Anemia Among Jazan University Students.International journal of general medicine · 2020Article
- Spectrum of hemoglobinopathies with hematological and biochemical profile: A five year experience from a tertiary care hospital.Pakistan journal of medical sciencesArticle
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Authors and funding
2 authors at 1 institution in 1 country.
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Abstract
objectivesTo evaluate the prevalence of undiagnosed hemoglobinopathies among individuals visiting the premarital screening Centre.
methodsThis study was conducted at Premarital Screening Centre, King Fahad Central Hospital and Research Centre, Jazan, between January 2018 and October 2018. A total of 3,970 (male n =1,859 and female n = 2,111) individuals were included in the study. Data of complete blood count, hemoglobin electrophoresis and sickling tests of all individuals recruited in the study were obtained and statistically analyzed.
resultsOne thousand three hundred and twelve individuals had abnormal complete blood counts or hemoglobin electrophoresis results, that include sickle cell trait (13.5%), sickle cell disease (0.7%), β thalassemia with sickle cell trait (2.46%), β thalassemia trait (1.51%), β thalassemia major (0.075%), suspected α thalassemia or other hemoglobinopathies (4.43%), hemoglobin H (0.3%), hemoglobin E (0.075%), undiagnosed cases (0.91%) and iron deficient (7.23%).
conclusionA high percentage of individuals are suspected for α thalassemia or other hemoglobinopathies that needs to be diagnosed. Further investigations shall be included in the premarital screening program to diagnose these inconclusive cases. Coexistence iron deficiency with thalassemia shall also be ruled out during premarital screening program.
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