Evidence map›Paper›PMID 31777422›Full record

ArticleJournal of clinical biochemistry and nutrition2019

Ascorbic acid insufficiency impairs spatial memory formation in juvenile AKR1A-knockout mice.

Kazuki Kurihara, Takujiro Homma, Sho Kobayashi, Mototada Shichiri, Hiroki Fujiwara, Satoshi Fujii, Ken-Ichi Yamada, Masaki Nakane, Kaneyuki Kawamae, Junichi Fujii

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical biochemistry and nutrition, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Ascorbate Is a Primary Antioxidant in Mammals.Molecules (Basel, Switzerland) · 2022
    Review
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  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Kazuki KuriharaDepartment of Biochemistry and Molecular Biology, Graduate School of Medical Science, Yamagata University, 2-2-2 Iidanishi, Yamagata 990-9585, Japan.
Takujiro HommaDepartment of Biochemistry and Molecular Biology, Graduate School of Medical Science, Yamagata University, 2-2-2 Iidanishi, Yamagata 990-9585, Japan.
Sho KobayashiDepartment of Biochemistry and Molecular Biology, Graduate School of Medical Science, Yamagata University, 2-2-2 Iidanishi, Yamagata 990-9585, Japan.
Mototada ShichiriBiomedical Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), 1-8-31 Midorigaoka, Ikeda, Osaka 563-8577, Japan.
Hiroki FujiwaraDepartment of Physiology, Faculty of Medicine, Yamagata University, 2-2-2 Iidanishi, Yamagata 990-9585, Japan.
Satoshi FujiiDepartment of Physiology, Faculty of Medicine, Yamagata University, 2-2-2 Iidanishi, Yamagata 990-9585, Japan.
Ken-Ichi YamadaPhysical Chemistry for Life Science Laboratory, Faculty of Pharmaceutical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan.
Masaki NakaneDepartment of Emergency and Critical Care Medicine, Faculty of Medicine, Yamagata University, 2-2-2 Iidanishi, Yamagata 990-9585, Japan.
Kaneyuki KawamaeDepartment of Anesthesiology, Faculty of Medicine, Yamagata University, 2-2-2 Iidanishi, Yamagata 990-9585, Japan.
Junichi FujiiDepartment of Biochemistry and Molecular Biology, Graduate School of Medical Science, Yamagata University, 2-2-2 Iidanishi, Yamagata 990-9585, Japan.
Yamagata University · JPLife Science Institute · JPNational Institute of Advanced Industrial Science and Technology · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

AKR1A, an aldo-keto reductase, is involved in the synthesis of ascorbic acid as well as the reduction of a variety of aldehyde compounds. AKR1A

Indexed as

AKR1Aascorbic acidMorris water mazespatial memory

Identifiers

PMID31777422
PMCPMC6877411
OpenAlexW2973064065

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.