Evidence map›Paper›PMID 31777046›Full record

ArticleAmerican journal of perinatology2020

Acute Kidney Injury and Bronchopulmonary Dysplasia in Premature Neonates Born Less than 32 Weeks' Gestation.

Michelle C Starr, Louis Boohaker, Laurie C Eldredge, Shina Menon, Russell Griffin, Dennis E Mayock, Linzi Li, David Askenazi, Sangeeta Hingorani, Neonatal Kidney Collaborative

Abstract read
In one paragraph

Article in American journal of perinatology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  5. Article
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  7. Kidney care at NICU discharge and follow-up recommendations for preterm infants<34 weeks.Journal of perinatology : official journal of the California Perinatal Association · 2026
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  16. Post-natal steroid exposure in very low birthweight neonates and associations with acute kidney injury.Journal of perinatology : official journal of the California Perinatal Association · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Michelle C StarrDepartment of Pediatrics, Division of Pediatric Nephrology, Indiana University School of Medicine, Indianapolis, Indiana.ORCID 0000-0001-9412-8950
Louis BoohakerDivision of Pediatric Nephrology, University of Alabama at Birmingham, Birmingham, Alabama.
Laurie C EldredgeDepartment of Pediatrics, Division of Pulmonology, Seattle Children's Hospital and University of Washington, Seattle, Washington.
Shina MenonDepartment of Pediatrics, Division of Nephrology, Seattle Children's Hospital and University of Washington, Seattle, Washington.
Russell GriffinDepartment of Epidemiology, University of Alabama at Birmingham, Birmingham, Alabama.
Dennis E MayockDepartment of Pediatrics, Division of Neonatology, University of Washington, Seattle, Washington.
Linzi LiDepartment of Epidemiology, University of Alabama at Birmingham, Birmingham, Alabama.
David AskenaziDivision of Pediatric Nephrology, University of Alabama at Birmingham, Birmingham, Alabama.
Sangeeta HingoraniDepartment of Pediatrics, Division of Nephrology, Seattle Children's Hospital and University of Washington, Seattle, Washington.
Neonatal Kidney Collaborative

Funding

UNM HSC Clinical and Translational Science CenterUL1TR001449 · NCATS · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI CAMPEN, MATTHEW J, PANDHI, NANCY · 2015 to 2024
$36.9M
UAB Center for Clinical and Translational Science (CCTS)UL1TR001417 · NCATS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI KIMBERLY, ROBERT P. · 2015 to 2018
$31.4M
Preterm Epo Neuroprotection Trial (PENUT Trial) CCCU01NS077953 · NINDS · UNIVERSITY OF WASHINGTON · PI JUUL, SANDRA E · 2013 to 2018
$10.7M
The University of Iowa Clinical and Translational Science AwardU54TR001356 · NCATS · UNIVERSITY OF IOWA · PI WINOKUR, PATRICIA · 2015 to 2016
$7.1M
Pediatric Nephrology Training ProgramT32DK007662 · NIDDK · UNIVERSITY OF WASHINGTON · PI HINGORANI, SANGEETA · 1991 to 2020
$5.5M
Recombinant Erythropoietin for Protection of Infant Renal Disease(REPAIReD)R01DK103608 · NIDDK · SEATTLE CHILDREN'S HOSPITAL · PI ASKENAZI, DAVID JOSEPH, GOLDSTEIN, STUART L · 2014 to 2019
$3.0M
Phase 2 Study of Selective Cytopheretic Device for the Treatment of Pediatric Patients with Acute Kidney Injury R01FD005092 · FDA · INNOVATIVE BIOTHERAPIES, INC. · PI GOLDSTEIN, STUART L, HUMES, H. DAVID · 2015 to 2018
$976k
FDA HHS R01 FD005092NCATS NIH HHS U54 TR001356NCATS NIH HHS UL1 TR001417NCATS NIH HHS UL1 TR001449NIDDK NIH HHS R01 DK103608NIDDK NIH HHS T32 DK007662NINDS NIH HHS U01 NS077953
6 · The paper itself

Abstract

objectiveThis study aimed to evaluate the association between acute kidney injury (AKI) and bronchopulmonary dysplasia (BPD) in infants born <32 weeks of gestational age (GA). STUDY

designPresent study is a secondary analysis of premature infants born at <32 weeks of GA in the Assessment of Worldwide Acute Kidney Injury Epidemiology in Neonates (AWAKEN) retrospective cohort (

resultsModerate or severe BPD occurred in 214 of 546 (39%) infants, while death occurred in 32 of 546 (6%); the composite of moderate or severe BPD/death occurred in 246 of 546 (45%). For infants born ≤29 weeks of gestation, the adjusted odds ratio (OR) of AKI and the primary outcome was 1.15 (95% confidence interval [CI] = 0.47-2.86;

conclusionNeonates born between 29 and 32 weeks who develop AKI had a higher likelihood of moderate or severe BPD/death than those without AKI. Further studies are needed to validate our findings and evaluate mechanisms of multiorgan injury.

Indexed as

Infant, Premature, DiseasesAcute Kidney InjuryBronchopulmonary DysplasiaFemaleGestational AgeHumansIncidenceInfant, NewbornInfant, PrematureLogistic ModelsMaleOdds RatioRetrospective Studies

Identifiers

PMID31777046
PMCPMC7409513

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.