ReviewClinical reviews in allergy & immunology2020
Innate-like Lymphocytes and Innate Lymphoid Cells in Asthma.
Review in Clinical reviews in allergy & immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 27 citations in OpenAlex.
- Systemic Immune Dysregulation in Allergic Rhinitis: Mechanisms, Comorbidities, and Implications for Targeted Therapy.Journal of asthma and allergy · 2026Review
- Pyroptosis, A Double-Edged Sword in Respiratory Diseases: A Narrative Review.Journal of inflammation research · 2026Review
- The relationship of Systemic Inflammatory Index with asthma in adults: A retrospective cross-sectional study.The Journal of international medical research · 2025Article
- Review
- Recurrence of acute allergic asthma depends on the role of ILC2 driven by Il1rl1 signaling.Cell communication and signaling : CCS · 2025Article
- Association between monocyte-high-density lipoprotein cholesterol ratio and mortality in a population with asthma: a cohort study.Lipids in health and disease · 2025Article
- Article
- Endothelial activation and stress index for prediction of mortality in asthma.Frontiers in medicine · 2025Article
- The Circadian Rhythm of Asthma Immune Metabolism.Journal of immunology research · 2025Review
- Antibody Fc-receptor FcεR1γ stabilizes cell surface receptors in group 3 innate lymphoid cells and promotes anti-infection immunity.Nature communications · 2024Article
- Bacterial lysate add-on therapy in adult and childhood asthma: a systematic review and meta-analysis.Journal of thoracic disease · 2023Article
- Impact of aging on immune function in the pathogenesis of pulmonary diseases: potential for therapeutic targets.Expert review of respiratory medicine · 2023Review
- Associations of complete blood cell count-derived inflammatory biomarkers with asthma and mortality in adults: a population-based study.Frontiers in immunology · 2023Article
- Comparative phenotype of circulating versus tissue immune cells in human lung and blood compartments during health and disease.Discovery immunology · 2023Article
- Role of the innate and adaptive immune responses in the pathogenesis of systemic lupus erythematosus.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2022Review
- Exploration of induced sputum BIRC3 levels and clinical implications in asthma.BMC pulmonary medicine · 2022Article
- IL-36 Cytokines: Their Roles in Asthma and Potential as a Therapeutic.Frontiers in immunology · 2022Review
- Majie Cataplasm Promotes Th1 Response to Fight against Asthmatic Th2 Inflammation through NKs.Evidence-based complementary and alternative medicine : eCAM · 2022Article
- The Role of Group 3 Innate Lymphoid Cells in Lung Infection and Immunity.Frontiers in cellular and infection microbiology · 2021Review
- Adrenergic regulation of immune cell function and inflammation.Seminars in immunopathology · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
Abstract
Asthma is a chronic pulmonary disease, highly associated with immune disorders. The typical symptoms of asthma include airway hyperresponsiveness (AHR), airway remodeling, mucus overproduction, and airflow limitation. The etiology of asthma is multifactorial and affected by genetic and environmental factors. Increasing trends toward dysbiosis, smoking, stress, air pollution, and a western lifestyle may account for the increasing incidence of asthma. Based on the presence or absence of eosinophilic inflammation, asthma is mainly divided into T helper 2 (Th2) and non-Th2 asthma. Th2 asthma is mediated by allergen-specific Th2 cells, and eosinophils activated by Th2 cells via the secretion of interleukin (IL)-4, IL-5, and IL-13. Different from Th2 asthma, non-Th2 asthma shows little eosinophilic inflammation, resists to corticosteroid treatment, and occurs mainly in severe asthmatic patients. Previous studies of asthma primarily focused on the function of Th2 cells, but, with the discovery of non-Th2 asthma and the involvement of innate lymphoid cells (ILCs) in the pathogenesis of asthma, tissue-resident innate immune cells in the lung have become the focus of attention in asthma research. Currently, innate-like lymphocytes (ILLs) and ILCs as important components of the innate immune system in mucosal tissues are reportedly involved in the pathogenesis of or protection against both Th2 and non-Th2 asthma. These findings of the functions of different subsets of ILLs and ILCs may provide clues for the treatment of asthma.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.