Evidence map›Paper›PMID 31776925›Full record

ReviewMethods in molecular biology (Clifton, N.J.)2020

An Overview of Advances in Cell-Based Cancer Immunotherapies Based on the Multiple Immune-Cancer Cell Interactions.

Jialing Zhang, Stephan S Späth, Sherman M Weissman, Samuel G Katz

Abstract readReview
In one paragraph

Review in Methods in molecular biology (Clifton, N.J.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jialing ZhangDepartment of Pathology, Yale School of Medicine, New Haven, CT, USA.
Stephan S SpäthUniversity of Tübingen, Tübingen, Germany.
Sherman M WeissmanDepartment of Genetics, Yale School of Medicine, New Haven, CT, USA.
Samuel G KatzDepartment of Pathology, Yale School of Medicine, New Haven, CT, USA. samuel.katz@yale.edu.

Funding

Cell Death Regulation by Pro-Apoptotic BOK in CardiomyocytesR01HL131793 · NHLBI · YALE UNIVERSITY · PI KATZ, SAMUEL G · 2016 to 2020
$2.3M
SYNERGIZING PRO-APOPTOTIC AND CAR-T CELL IMMUNOTHERAPY FOR MANTLE CELL LYMPHOMAR21CA198561 · NCI · YALE UNIVERSITY · PI KATZ, SAMUEL G · 2015 to 2016
$398k
NCI NIH HHS R21 CA198561NHLBI NIH HHS R01 HL131793
6 · The paper itself

Abstract

Tumors have a complex ecosystem in which behavior and fate are determined by the interaction of diverse cancerous and noncancerous cells at local and systemic levels. A number of studies indicate that various immune cells participate in tumor development (Fig. 1). In this review, we will discuss interactions among T lymphocytes (T cells), B cells, natural killer (NK) cells, dendritic cells (DCs), tumor-associated macrophages (TAMs), neutrophils, and myeloid-derived suppressor cells (MDSCs). In addition, we will touch upon attempts to either use or block subsets of immune cells to target cancer.

Indexed as

Cell CommunicationImmunotherapyAnimalsHumansLymphocytesModels, BiologicalNeoplasmsAdoptive cell therapyImmune cellsImmunotherapy

Identifiers

PMID31776925
PMCPMC7062409

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.