ReviewEuropean journal of applied physiology2020
Historical reviews of the assessment of human cardiovascular function: interrogation and understanding of the control of skin blood flow.
Review in European journal of applied physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 57 citations in OpenAlex.
- Non-Invasive Assessment of Endothelial Dysfunction and Arterial Stiffness in Fontan Circulation.European journal of clinical investigation · 2026Review
- Cutaneous Microvascular Functional Reserve is Associated with Kidney Function and Histopathologic Injury in CKD: The MAP-CKD Study.medRxiv : the preprint server for health sciences · 2026Article
- Homeostatic Responses to Subsystolic Arterial Occlusive Pressure in Glabrous and Non-Glabrous Skin Circulation.Biomedicines · 2026Article
- Optimizing In Vivo Perfusion Assessment by Laser Doppler Flowmetry-Effects of Probe Geometry and Signal Normalization.Diagnostics (Basel, Switzerland) · 2026Article
- A Brand-New Drainage Fluid Predictor, ICAM-1 for Implant Loss After the Immediate Reconstruction of Breast.Breast cancer (Dove Medical Press) · 2026Article
- Quantifying microvascular responses to local heating using optical coherence tomography: Comparison between skin sites and sex differences.Experimental physiology · 2025Article
- Endothelial dysfunction in chronic kidney disease: a clinical perspective.American journal of physiology. Heart and circulatory physiology · 2025Review
- The Altered Vascular Endothelial Control of Facial Cutaneous Blood Flow in Rosacea.Acta dermato-venereologica · 2025Article
- Monitoring microvascular changes over time with a repositionable 3D ultrasonic capacitive micromachined row-column sensor.Science advances · 2025Article
- The clinical effects and skin histological changes induced by a novel insulated radiofrequency microneedle: a pilot study.Lasers in medical science · 2025Article
- Cutaneous Wound Healing and the Effects of Cannabidiol.International journal of molecular sciences · 2024Review
- Lower-Limb Perfusion and Cardiovascular Physiology Are Significantly Improved in Non-Healthy Aged Adults by Regular Home-Based Physical Activities-An Exploratory Study.Life (Basel, Switzerland) · 2024Article
- A century of exercise physiology: concepts that ignited the study of human thermoregulation. Part 2: physiological measurements.European journal of applied physiology · 2023Review
- Assessing aerobic physical efficiency through temple surface temperature measurements during light, heavy exercise, and recovery.Scientific reports · 2023Article
- Human temperature regulation under heat stress in health, disease, and injury.Physiological reviews · 2022Review
- Visualising and quantifying microvascular structure and function in patients with heart failure using optical coherence tomography.The Journal of physiology · 2022Article
- Remote ischaemic preconditioning - translating cardiovascular benefits to humans.The Journal of physiology · 2022Review
- Methods to evaluate vascular function: a crucial approach towards predictive, preventive, and personalised medicine.The EPMA journal · 2022Review
- Skin-on-a-Chip Technology: Microengineering Physiologically Relevant In Vitro Skin Models.Pharmaceutics · 2022Review
- Skin Microhemodynamics and Mechanisms of Its Regulation in Type 2 Diabetes Mellitus.Biophysics · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Several techniques exist for the determination of skin blood flow that have historically been used in the investigation of thermoregulatory control of skin blood flow, and more recently, in clinical assessments or as an index of global vascular function. Skin blood flow measurement techniques differ in their methodology and their strengths and limitations. To examine the historical development of techniques for assessing skin blood flow by describing the origin, basic principles, and important aspects of each procedure and to provide recommendations for best practise. Venous occlusion plethysmography was one of the earliest techniques to intermittently index a limb's skin blood flow under conditions in which local muscle blood flow does not change. The introduction of laser Doppler flowmetry provided a method that continuously records an index of skin blood flow (red cell flux) (albeit from a relatively small skin area) that requires normalisation due to high site-to-site variability. The subsequent development of laser Doppler and laser speckle imaging techniques allows the mapping of skin blood flow from larger surface areas and the visualisation of capillary filling from the dermal plexus in two dimensions. The use of iontophoresis or intradermal microdialysis in conjunction with laser Doppler methods allows for the local delivery of pharmacological agents to interrogate the local and neural control of skin blood flow. The recent development of optical coherence tomography promises further advances in assessment of the skin circulation via three-dimensional imaging of the skin microvasculature for quantification of vessel diameter and vessel recruitment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.