ArticleScientific reports2019
Anti-biofilm effects and characterisation of the hydrogen peroxide activity of a range of Western Australian honeys compared to Manuka and multifloral honeys.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 58 citations in OpenAlex.
- Medicinal Honeys from Oceania: An Updated Review on Their Bioactive Constituents and Health Applications.Biotech (Basel (Switzerland)) · 2026Review
- Unveiling the phytochemical profiles ofFood chemistry: X · 2025Article
- Povidone-Iodine and Hydrogen Peroxide Combination Improves the Anti-Biofilm Activity of the Individual Agents onInternational journal of molecular sciences · 2025Article
- Hydrogen Peroxide: A Ubiquitous Component of Beverages and Food.International journal of molecular sciences · 2025Review
- Bioactive Compounds, Antioxidant Properties, and Antimicrobial Profiling of a Range of West Algerian Honeys: In Vitro Comparative Screening Prior to Therapeutic Purpose.Foods (Basel, Switzerland) · 2024Article
- Design, Synthesis, Molecular Docking, and ADME-Tox Investigations of Imidazo[1,2-a]Pyrimidines Derivatives as Antimicrobial Agents.Molecules (Basel, Switzerland) · 2024Article
- Antibacterial activity of Hungarian varietal honeys against respiratory pathogens as a function of storage time.Scientific reports · 2024Article
- Bioactive Dressing: A New Algorithm in Wound Healing.Journal of clinical medicine · 2024Review
- In Vitro Prebiotic Effects and Antibacterial Activity of Five Leguminous Honeys.Foods (Basel, Switzerland) · 2023Article
- Antibiofilm, Antimicrobial, Anti-Quorum Sensing, and Antioxidant Activities of Saudi Sidr Honey: In Vitro and Molecular Docking Studies.Pharmaceutics · 2023Article
- Design, Preparation, and Physicochemical Characterisation of Alginate-Based Honey-Loaded Topical Formulations.Pharmaceutics · 2023Article
- Beyond the Risk of Biofilms: An Up-and-Coming Battleground of Bacterial Life and Potential Antibiofilm Agents.Life (Basel, Switzerland) · 2023Review
- Characterisation of physicochemical parameters and antibacterial properties of New Caledonian honeys.PloS one · 2023Article
- A Comprehensive HPTLC-Based Analysis of the Impacts of Temperature on the Chemical Properties and Antioxidant Activity of Honey.Molecules (Basel, Switzerland) · 2022Article
- Anti-Inflammatory and Antibacterial Effects and Mode of Action of Greek Arbutus, Chestnut, and Fir Honey in Mouse Models of Inflammation and Sepsis.Microorganisms · 2022Article
- Antibacterial interactions between two monofloral honeys and several topical antiseptics, including essential oils.BMC complementary medicine and therapies · 2022Article
- A Review of Commonly Used Methodologies for Assessing the Antibacterial Activity of Honey and Honey Products.Antibiotics (Basel, Switzerland) · 2022Review
- Australian Honeypot Ant (Molecules (Basel, Switzerland) · 2022Article
- An investigation of the suitability of melissopalynology to authenticate Jarrah honey.Current research in food science · 2022Article
- Role of Honey in Advanced Wound Care.Molecules (Basel, Switzerland) · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The antibacterial activity of honeys derived from the endemic flora of the southwest corner of Western Australia, including the trees Jarrah (Eucalyptus marginata) and Marri (Corymbia calophylla), remains largely unexplored. Investigation of these honeys showed minimum inhibitory concentrations (MICs) of 6.7-28.0% (w/v) against Gram positive and negative bacteria. Honey solutions showed enhanced antibacterial activity after hydrogen peroxide was allowed to accumulate prior to testing, with a mean MIC after accumulation of 14.3% compared to 17.4% before accumulation. Antibacterial activity was reduced after treatment with catalase enzyme, with a mean MIC of 29.4% with catalase compared to 15.2% without catalase. Tests investigating the role of the Gram negative outer membrane in honey susceptibility revealed increases in activity after destabilisation of the outer membrane. Honeys reduced both the formation of biofilm and the production of bacterial pigments, which are both regulated by quorum sensing. However, these reductions were closely correlated with global growth inhibition. Honey applied to existing biofilms resulted in decreased metabolic activity and minor decreases in viability. These results enhance our understanding of the mechanisms of antibacterial action of Jarrah and Marri honeys, and provide further support for the use of honey in the treatment of infected wounds.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.