Trial reportScientific reports2019
The Effect of Strict Volume Control Assessed by Repeated Bioimpedance Spectroscopy on Cardiac Function in Peritoneal Dialysis Patients.
Trial report in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04556123 (Bioimpedance Guided Management of Patients Scheduled for Transcatheter Aortic Valve Replacement), which is not on this map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Bioimpedance Guided Management of Patients Scheduled for Transcatheter Aortic Valve Replacement: A Randomized Controlled Trial.
Who cites it
13 citing papers in PubMed, 14 citations in OpenAlex.
- Nighttime Systolic Blood Pressure and Cardiovascular and All-Cause Mortality in Peritoneal Dialysis Patients: A Single-Center Prospective Cohort Study.Journal of clinical medicine · 2026Article
- Best Evidence Summary for Volume Management of Patients With Heart and Kidney Comorbidity.Nursing open · 2026Review
- Analysis of biological systems using bioimpedance spectroscopy: a critical review of technological convergence and translational challenges.Frontiers in bioengineering and biotechnology · 2026Review
- The Efficacy and Safety of Technology-Guided Dry Weight Adjustment Among Dialysis Patients: A Meta-analysis of Randomized Controlled Trials.Kidney medicine · 2025Article
- Benefits of SGLT2 inhibitors in patients with diabetes and advanced chronic kidney disease - where have we gone so far?Frontiers in clinical diabetes and healthcare · 2025Review
- Evidence Summary of Personalized Management of Peritoneal Dialysis Volume in Adults.Journal of multidisciplinary healthcare · 2025Review
- Comparison of bioimpedance equations and dual-energy X-ray for assessment of fat free mass in a Chinese dialysis population.Renal failure · 2023Article
- Volume markers in left ventricular diastolic dysfunction and adverse outcomes in peritoneal dialysis patients: a prospective cohort study.Scientific reports · 2023Article
- Optimization of the Chronic Kidney Disease-Peritoneal Dialysis App to Improve Care for Patients on Peritoneal Dialysis in Northeast Thailand: User-Centered Design Study.JMIR formative research · 2022Article
- Fluid overload in patients undergoing TAVR: what we can learn from the nephrologists.ESC heart failure · 2021Article
- Changes in extracellular water and left ventricular mass in peritoneal dialysis patients.Kidney research and clinical practice · 2021Article
- Effect of volume indices of bioimpedance analysis on clinical outcomes, including left ventricular hypertrophy, in patients undergoing peritoneal dialysis.Kidney research and clinical practice · 2021Article
- Bioimpedance spectroscopy: Is a picture worth a thousand words?Seminars in dialysisArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors at 6 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Adequate fluid management plays an important role in decreasing cardiovascular risk in peritoneal dialysis (PD) patients. We evaluated whether strict volume control monitored by bioimpedance spectroscopy (BIS) affects cardiac function in PD patients. This study is a secondary analysis of a multicentre, prospective, randomized, controlled trial. Fluid overload was assessed by the average overhydration/extracellular water (OH/ECW) at baseline, 6 months and 12 months. Patients were categorized as time-averaged overhydrated (TA-OH/ECW ≥15%) or normohydrated (TA-OH/ECW <15%), and echocardiographic parameters were compared between groups. Among a total of 151 patients, 120 patients exhibited time-averaged normohydration. Time-averaged overhydrated patients had a significantly higher left atrial (LA) diameter and E/e' ratio and a lower left ventricular (LV) ejection fraction at 12 months than time-averaged normohydrated patients. LA diameter, end-systolic volume and end-diastolic volume were decreased at 12 months compared to baseline in time-averaged normohydrated patients only. TA-OH/ECW was independently associated with ejection fraction at 12 months (β = -0.190; p = 0.010). TA-OH/ECW, but not OH/ECW at 12 months, was an independent risk factor for LV dysfunction (odds ratio 4.020 [95% confidence interval 1.285-12.573]). Overhydration status based on repeated BIS measurements is an independent predictor of LV systolic function in PD patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.