ArticleProceedings of the National Academy of Sciences of the United States of America2019
Critical role for TRIM28 and HP1β/γ in the epigenetic control of T cell metabolic reprograming and effector differentiation.
Open access · bronzeAbstract read
In one paragraph
Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
31 citing papers in PubMed, 38 citations in OpenAlex.
- TRIM28 and TRIM32: multifaceted regulators of innate immunity and antiviral defence.Immunologic research · 2026Review
- Metabolic modulation of immune cell function: mechanisms and therapeutic implications in cancer immunotherapy.Oncogenesis · 2026Review
- Cytoplasmic translocation of tripartite motif-containing 28 is critical for PRRSV-induced autophagy through promoting Vps34-Beclin1 complex formation.Journal of virology · 2025Article
- Metabolic reprogram and T cell differentiation in inflammation: current evidence and future perspectives.Cell death discovery · 2025Review
- TRIM28 is an essential regulator of three-dimensional chromatin state underpinning CD8Nature communications · 2025Article
- Heterochromatic gene silencing controls CD4Nature communications · 2025Article
- Single-cell RNA sequencing uncovers intestinal immune alterations and cellular diversity from chronic fluoride exposure in mice.Theranostics · 2025Article
- TRIM28 mediates Mettl5 ubiquitination to promotes Th2 polarization.Frontiers in immunology · 2025Article
- Multifaceted role ofMedComm · 2024Review
- Enhanced Transcription of Human Endogenous Retroviruses and TRIM28 Downregulation in Patients with Inflammatory Bowel Disease.Viruses · 2024Article
- Set7/9 aggravates ischemic brain injury via enhancing glutamine metabolism in a blocking Sirt5 manner.Cell death and differentiation · 2024Article
- Advances in research on the role of high carbohydrate diet in the process of inflammatory bowel disease (IBD).Frontiers in immunology · 2024Review
- The Immune Modulatory Role of TIF1 Proteins.Advances in experimental medicine and biology · 2024Review
- TRIM28 in cancer and cancer therapy.Frontiers in genetics · 2024Review
- TRIM28 modulates nuclear receptor signaling to regulate uterine function.Nature communications · 2023Article
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- Trim28 citrullination maintains mouse embryonic stem cell pluripotency via regulating Nanog and Klf4 transcription.Science China. Life sciences · 2023Article
- Expressions of Type I and III Interferons, Endogenous Retroviruses, TRIM28, and SETDB1 in Children with Respiratory Syncytial Virus Bronchiolitis.Current issues in molecular biology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
28 authors at 5 institutions in 4 countries.
Ulf GehrmannInstitut Curie, Université Paris Sciences et Lettres, INSERM U932, 75005 Paris, France; ulf.gehrmann@astrazeneca.com sebastian.amigorena@curie.fr.ORCID 0000-0001-6942-5355
Marianne BurbageInstitut Curie, Université Paris Sciences et Lettres, INSERM U932, 75005 Paris, France.ORCID 0000-0003-0686-2608
Elina ZuevaInstitut Curie, Université Paris Sciences et Lettres, INSERM U932, 75005 Paris, France.
Christel GoudotInstitut Curie, Université Paris Sciences et Lettres, INSERM U932, 75005 Paris, France.
Cyril EsnaultInstitute de Génétique Moléculaire de Montpellier, University of Montpellier, CNRS, 34094 Montpellier, France.
Mengliang YeInstitut Curie, Université Paris Sciences et Lettres, INSERM U932, 75005 Paris, France.
Jean-Marie CarpierInstitut Curie, Université Paris Sciences et Lettres, INSERM U932, 75005 Paris, France.
Nina BurgdorfInstitut Curie, Université Paris Sciences et Lettres, INSERM U932, 75005 Paris, France.
Thomas HoylerInstitut Curie, Université Paris Sciences et Lettres, INSERM U932, 75005 Paris, France.
Guadalupe SuarezInstitut Curie, Université Paris Sciences et Lettres, INSERM U932, 75005 Paris, France.
Leonel JoannasInstitut Curie, Université Paris Sciences et Lettres, INSERM U932, 75005 Paris, France.
Sandrine Heurtebise-ChrétienInstitut Curie, Université Paris Sciences et Lettres, INSERM U932, 75005 Paris, France.
Sylvère DurandInstitut Gustave Roussy, Plateforme Métabolomique/UMR1138, 94800 Villejuif, France.
Rébecca PanesFaculté de Médecine, Département de Microbiologie, Infectiologie et Immunologie, Université de Montréal, Montréal, QC H3T 1J4, Canada.
Angélique Bellemare-PelletierAxe de Recherche en Immunobiologie du Cancer, Institut de Recherche en Immunologie et Cancérologie, Montréal, QC H3T 1J4, Canada.
Pablo J SáezInstitut Curie, Université Paris Sciences et Lettres, INSERM U932, 75005 Paris, France.
Fanny AprahamianInstitut Gustave Roussy, Plateforme Métabolomique/UMR1138, 94800 Villejuif, France.
Deborah LefevreInstitut Gustave Roussy, Plateforme Métabolomique/UMR1138, 94800 Villejuif, France.
Veronique AdoueCNRS, Centre de Physiopathologie de Toulouse Purpan, Université de Toulouse, Université Paul Sabatier, 31330 Toulouse, France.
Amal Zine El AabidineInstitute de Génétique Moléculaire de Montpellier, University of Montpellier, CNRS, 34094 Montpellier, France.
Maqbool Muhammad AhmadInstitute de Génétique Moléculaire de Montpellier, University of Montpellier, CNRS, 34094 Montpellier, France.
Claire HivrozInstitut Curie, Université Paris Sciences et Lettres, INSERM U932, 75005 Paris, France.
Olivier JoffreINSERM U1043, Centre de Physiopathologie de Toulouse Purpan, Université de Toulouse, Université Paul Sabatier, 31330 Toulouse, France.ORCID 0000-0003-1168-8165
Florence CammasInstitut de Recherche en Cancérologie de Montpellier, INSERM U1194, Université Montpellier, 34298 Montpellier, France.ORCID 0000-0003-4117-8182
Guido KroemerInstitut Gustave Roussy, Plateforme Métabolomique/UMR1138, 94800 Villejuif, France.
Etienne GagnonFaculté de Médecine, Département de Microbiologie, Infectiologie et Immunologie, Université de Montréal, Montréal, QC H3T 1J4, Canada.ORCID 0000-0001-5815-9768
Jean-Christophe AndrauInstitute de Génétique Moléculaire de Montpellier, University of Montpellier, CNRS, 34094 Montpellier, France.
Sebastian AmigorenaInstitut Curie, Université Paris Sciences et Lettres, INSERM U932, 75005 Paris, France; ulf.gehrmann@astrazeneca.com sebastian.amigorena@curie.fr.
Inserm · FRCentre National de la Recherche Scientifique · FRInstitute for Research in Immunology and Cancer · CAKarolinska University Hospital · SEUniversité Toulouse III - Paul Sabatier · FR
Funding
No grant is acknowledged in the PubMed record.
Abstract
Naive CD4
Indexed as
AnimalsAutoimmunityCD4-Positive T-LymphocytesCell DifferentiationCell PlasticityCellular ReprogrammingChromobox Protein Homolog 5Chromosomal Proteins, Non-HistoneColonCytokinesDNA-Binding ProteinsEpigenesis, GeneticGene Expression RegulationGene SilencingHistonesMiceCbx1 protein, mouseChromobox Protein Homolog 5Chromosomal Proteins, Non-HistoneCytokinesDNA-Binding ProteinsHistonesPhosphatidylinositol 3-KinasesRag2 protein, mouseReceptors, Antigen, T-CellTrim28 protein, mouseTripartite Motif-Containing Protein 28autoimmunityepigeneticsimmunologyT cellsTRIM28
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.