Evidence map›Paper›PMID 31776239›Full record

ArticlemSphere2019

Rapid Bladder Interleukin-10 Synthesis in Response to Uropathogenic Escherichia coli Is Part of a Defense Strategy Triggered by the Major Bacterial Flagellar Filament FliC and Contingent on TLR5.

Dhruba Acharya, Matthew J Sullivan, Benjamin L Duell, Kelvin G K Goh, Lahiru Katupitiya, Dean Gosling, Michelle N Chamoun, Asha Kakkanat, Debasish Chattopadhyay, Michael Crowley and 3 more

Open access · goldAbstract read
In one paragraph

Article in mSphere, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Virulence regulation in the fish pathogenFrontiers in cellular and infection microbiology · 2026
    Review
  3. Loss of Type 1 Pili and Flagella in UropathogenicPathogens (Basel, Switzerland) · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Immune defenses in the urinary tract.Trends in immunology · 2023
    Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Dhruba AcharyaSchool of Medical Sciences and Menzies Health Institute Queensland, Griffith University, Parklands, Australia.
Matthew J SullivanSchool of Medical Sciences and Menzies Health Institute Queensland, Griffith University, Parklands, Australia.ORCID 0000-0003-2276-3132
Benjamin L DuellSchool of Medical Sciences and Menzies Health Institute Queensland, Griffith University, Parklands, Australia.
Kelvin G K GohSchool of Medical Sciences and Menzies Health Institute Queensland, Griffith University, Parklands, Australia.ORCID 0000-0001-8347-2043
Lahiru KatupitiyaSchool of Medical Sciences and Menzies Health Institute Queensland, Griffith University, Parklands, Australia.
Dean GoslingSchool of Medical Sciences and Menzies Health Institute Queensland, Griffith University, Parklands, Australia.
Michelle N ChamounSchool of Medical Sciences and Menzies Health Institute Queensland, Griffith University, Parklands, Australia.
Asha KakkanatSchool of Chemistry and Molecular Biosciences, University of Queensland, Brisbane, Australia.
Debasish ChattopadhyaySchool of Medicine, Division of Infectious Diseases, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Michael CrowleyHeflin Center for Genomic Sciences, University of Alabama at Birmingham, Birmingham, Alabama, USA.
David K CrossmanHeflin Center for Genomic Sciences, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Mark A SchembriSchool of Chemistry and Molecular Biosciences, University of Queensland, Brisbane, Australia.ORCID 0000-0003-4863-9260
Glen C UlettSchool of Medical Sciences and Menzies Health Institute Queensland, Griffith University, Parklands, Australia g.ulett@griffith.edu.au.ORCID 0000-0002-9638-8091
Griffith University · AUUniversity of Alabama at Birmingham · USThe University of Queensland · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Urinary tract infection (UTI) caused by uropathogenic

Indexed as

AnimalsCell LineDisease Models, AnimalEpithelial CellsEscherichia coli InfectionsEscherichia coli ProteinsFlagellinGene Expression ProfilingHumansImmunity, InnateInterleukin-10Mice, Inbred C57BLModels, TheoreticalTime FactorsToll-Like Receptor 5Urinary BladderEscherichia coli ProteinsFlagellinFliC protein, E coliIL10 protein, humanIL10 protein, mouseInterleukin-10TLR5 protein, humanTlr5 protein, mouseToll-Like Receptor 5flagellaurinary tract infectionuropathogenic Escherichia coli

Identifiers

PMID31776239
PMCPMC6881718
OpenAlexW2991323459

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.