Evidence map›Paper›PMID 31776212›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2020

Rod Photoreceptors Signal Fast Changes in Daylight Levels Using a Cx36-Independent Retinal Pathway in Mouse.

Rose Pasquale, Yumiko Umino, Eduardo Solessio

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. The Retinal Light Response Is Modulated by an mGluR5-Mediated Retrograde Signal from ON-Bipolar Cells to Photoreceptors.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Article
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  13. Interphotoreceptor coupling: an evolutionary perspective.Pflugers Archiv : European journal of physiology · 2021
    Review
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  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Rose PasqualeCenter for Vision Research, Department of Ophthalmology, SUNY Upstate Medical University, Syracuse, New York 13210.
Yumiko UminoCenter for Vision Research, Department of Ophthalmology, SUNY Upstate Medical University, Syracuse, New York 13210.
Eduardo SolessioCenter for Vision Research, Department of Ophthalmology, SUNY Upstate Medical University, Syracuse, New York 13210 solessie@upstate.edu.
SUNY Upstate Medical University · US

Funding

Contribution of rod photoresponse inactivation kinetics to visual temporal contrast sensitivity in mesopic light.R01EY026216 · NEI · UPSTATE MEDICAL UNIVERSITY · PI SOLESSIO, EDUARDO C · 2016 to 2025
$3.5M
NEI NIH HHS R01 EY026216
6 · The paper itself

Abstract

Temporal contrast detected by rod photoreceptors is channeled into multiple retinal rod pathways that ultimately connect to cone photoreceptor pathways via Cx36 gap junctions or via chemical synapses. However, we do not yet understand how the different rod pathways contribute to the perception of temporal contrast (changes in luminance with time) at mesopic light levels, where both rods and cones actively respond to light. Here, we use a forced-choice, operant behavior assay to investigate rod-driven, temporal contrast sensitivity (TCS) in mice of either sex. Transgenic mice with desensitized cones (GNAT2

Indexed as

AnimalsBehavior, AnimalChoice BehaviorContrast SensitivityFemaleLightMaleMiceMice, TransgenicPhotic StimulationRetinaRetinal Rod Photoreceptor CellsSignal TransductionVision, OcularVisual Perceptiongap junctionsmesopic visionmouse visionoperant behaviorrod pathwaystemporal contrast sensitivity

Identifiers

PMID31776212
PMCPMC6975299
OpenAlexW2990667122

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.