Evidence map›Paper›PMID 31776169›Full record

ArticleGenetics2020

SLC17A6/7/8 Vesicular Glutamate Transporter Homologs in Nematodes.

Esther Serrano-Saiz, Merly C Vogt, Sagi Levy, Yu Wang, Karolina K Kaczmarczyk, Xue Mei, Ge Bai, Andrew Singson, Barth D Grant, Oliver Hobert

Open access · bronzeAbstract read
In one paragraph

Article in Genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. A neurotransmitter atlas ofbioRxiv : the preprint server for biology · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Xenobiotic metabolism and transport inJournal of toxicology and environmental health. Part B, Critical reviews · 2021
    Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Esther Serrano-SaizDepartment of Biological Sciences, Columbia University, Howard Hughes Medical Institute, New York, New York 10027 esther.serrano.saiz@gmail.com.ORCID 0000-0003-0077-878X
Merly C VogtDepartment of Biological Sciences, Columbia University, Howard Hughes Medical Institute, New York, New York 10027.
Sagi LevyRockefeller University, New York, New York 10065.
Yu WangDepartment of Molecular Biology and Biochemistry, Rutgers University, Piscataway, New Jersey 08854.
Karolina K KaczmarczykDepartment of Biological Sciences, Columbia University, Howard Hughes Medical Institute, New York, New York 10027.
Xue MeiWaksman Institute, Rutgers University, Piscataway, New Jersey 08854.
Ge BaiDepartment of Molecular Biology and Biochemistry, Rutgers University, Piscataway, New Jersey 08854.
Andrew SingsonWaksman Institute, Rutgers University, Piscataway, New Jersey 08854.ORCID 0000-0002-5091-0892
Barth D GrantDepartment of Molecular Biology and Biochemistry, Rutgers University, Piscataway, New Jersey 08854.ORCID 0000-0002-5943-8336
Oliver HobertDepartment of Biological Sciences, Columbia University, Howard Hughes Medical Institute, New York, New York 10027.ORCID 0000-0002-7634-2854
Rutgers, The State University of New Jersey · USColumbia University · USConsejo Superior de Investigaciones Científicas · ESHoward Hughes Medical Institute · USRockefeller University · US

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5M
Membrane Traffic in C. elegans and MammalsR01GM067237 · NIGMS · RUTGERS THE ST UNIV OF NJ NEW BRUNSWICK · PI GRANT, BARTH DEMIAN · 2003 to 2019
$6.1M
[RNW] - Gamete Interactions in Caenorhabditis elegansR01HD054681 · NICHD · RUTGERS, THE STATE UNIV OF N.J. · PI ANDREW W. SINGSON · 2008 to 2026
$5.3M
Gamete Interactions in Caenorhabditis elegansR56HD054681 · NICHD · RUTGERS, THE STATE UNIV OF N.J. · PI SINGSON, ANDREW W · 2007 to 2007
$386k
Howard Hughes Medical InstituteNICHD NIH HHS R01 HD054681NICHD NIH HHS R56 HD054681NIGMS NIH HHS R01 GM067237NIH HHS P40 OD010440
6 · The paper itself

Abstract

Members of the superfamily of solute carrier (SLC) transmembrane proteins transport diverse substrates across distinct cellular membranes. Three SLC protein families transport distinct neurotransmitters into synaptic vesicles to enable synaptic transmission in the nervous system. Among them is the SLC17A6/7/8 family of vesicular glutamate transporters, which endows specific neuronal cell types with the ability to use glutamate as a neurotransmitter. The genome of the nematode

Indexed as

Amino Acid SequenceAnimalsAnimals, Genetically ModifiedBiological TransportCaenorhabditis elegansCaenorhabditis elegans ProteinsGenomeGlutamic AcidHumansNeuronsPhylogenySequence HomologySynaptic TransmissionSynaptic VesiclesVesicular Glutamate Transport ProteinsCaenorhabditis elegans ProteinsGlutamic AcidVesicular Glutamate Transport ProteinsC. elegansneurotransmittervesicular transporter

Identifiers

PMID31776169
PMCPMC6944403
OpenAlexW2990702046

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.