ArticleBMC plant biology2019
The grapevine homeobox gene VvHB58 influences seed and fruit development through multiple hormonal signaling pathways.
Article in BMC plant biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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18 citing papers in PubMed, 42 citations in OpenAlex.
- Pangenomic analyses in the cultivated grapevine confirm high genomic collinearity and extensive dispensable gene content likely involved in adaptation.G3 (Bethesda, Md.) · 2026Article
- GAFoods (Basel, Switzerland) · 2025Article
- Genomic prediction and association analyses for breeding parthenocarpic blueberries.Horticulture research · 2025Article
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- Genome-wide identification of B-box zinc finger (BBX) gene family in Medicago sativa and their roles in abiotic stress responses.BMC genomics · 2024Article
- Evolutionary Consequences of Functional and Regulatory Divergence of HD-Zip I Transcription Factors as a Source of Diversity in Protein Interaction Networks in Plants.Journal of molecular evolution · 2023Review
- Integrated microRNA and transcriptome profiling reveals the regulatory network of embryo abortion in jujube.Tree physiology · 2023Article
- Construction of a high density genetic linkage map to define the locus conferring seedlessness from Mukaku Kishu mandarin.Frontiers in plant science · 2023Article
- Fine mapping of the major geneFrontiers in plant science · 2023Article
- Article
- Genome-Wide Analysis of KNOX Transcription Factors and Expression Pattern of Dwarf-RelatedFrontiers in plant science · 2022Article
- Elevated transcription of transposable elements is accompanied by het-siRNA-driven de novo DNA methylation in grapevine embryogenic callus.BMC genomics · 2021Article
- VvHDZ28 positively regulate salicylic acid biosynthesis during seed abortion in Thompson Seedless.Plant biotechnology journal · 2021Article
- Review
- Genome-wide identification and expression analysis of the B-box transcription factor gene family in grapevine (Vitis vinifera L.).BMC genomics · 2021Article
- A moso bamboo transcription factor, Phehdz1, positively regulates the drought stress response of transgenic rice.Plant cell reports · 2021Article
- Genome-Wide Characterization and Expression Profiling of GASA Genes during Different Stages of Seed Development in Grapevine (International journal of molecular sciences · 2020Article
- Quantitative Trait Loci for Seed Size Variation in Cucurbits - A Review.Frontiers in plant science · 2020Review
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
Abstract
backgroundThe homeobox transcription factor has a diversity of functions during plant growth and development process. Previous transcriptome analyses of seed development in grape hybrids suggested that specific homeodomain transcription factors are involved in seed development in seedless cultivars. However, the molecular mechanism of homeobox gene regulating seed development in grape is rarely reported.
resultsHere, we report that the grapevine VvHB58 gene, encoding a homeodomain-leucine zipper (HD-Zip I) transcription factor, participates in regulating fruit size and seed number. The VvHB58 gene was differentially expressed during seed development between seedless and seeded cultivars. Subcellular localization assays revealed that the VvHB58 protein was located in the nucleus. Transgenic expression of VvHB58 in tomato led to loss of apical dominance, a reduction in fruit pericarp expansion, reduced fruit size and seed number, and larger endosperm cells. Analysis of the cytosine methylation levels within the VvHB58 promoter indicated that the differential expression during seed development between seedless and seeded grapes may be caused by different transcriptional regulatory mechanisms rather than promoter DNA methylation. Measurements of five classic endogenous hormones and expression analysis of hormone-related genes between VvHB58 transgenic and nontransgenic control plants showed that expression of VvHB58 resulted in significant changes in auxin, gibberellin and ethylene signaling pathways. Additionally, several DNA methylation-related genes were expressed differentially during seed development stages in seedless and seeded grapes, suggesting changes in methylation levels during seed development may be associated with seed abortion.
conclusionVvHB58 has a potential function in regulating fruit and seed development by impacting multiple hormonal pathways. These results expand understanding of homeodomain transcription factors and potential regulatory mechanism of seed development in grapevine, and provided insights into molecular breeding for grapes.
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