Evidence map›Paper›PMID 31775396›Full record

Trial reportNutrients2019

An Anthocyanin-Rich Mixed-Berry Intervention May Improve Insulin Sensitivity in a Randomized Trial of Overweight and Obese Adults.

Patrick M Solverson, Theresa R Henderson, Hawi Debelo, Mario G Ferruzzi, David J Baer, Janet A Novotny

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Review
  6. Review
  7. Review
  8. Review
  9. Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Review
  15. Review
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Patrick M SolversonUSDA, ARS, Beltsville Human Nutrition Research Center, Beltsville, MD 20705, USA.
Theresa R HendersonUSDA, ARS, Beltsville Human Nutrition Research Center, Beltsville, MD 20705, USA.
Hawi DebeloPlants for Human Health Institute, North Carolina State University, Kannapolis, NC 28081, USA.
Mario G FerruzziPlants for Human Health Institute, North Carolina State University, Kannapolis, NC 28081, USA.
David J BaerUSDA, ARS, Beltsville Human Nutrition Research Center, Beltsville, MD 20705, USA.
Janet A NovotnyUSDA, ARS, Beltsville Human Nutrition Research Center, Beltsville, MD 20705, USA.
Beltsville Human Nutrition Research Center · USNorth Carolina State University · USUniversity of Maryland, College Park · US

Funding

National Institute of Food and Agriculture 2014-67017-21837U.S. Department of Agriculture 8040-51000-056-00D
6 · The paper itself

Abstract

Evidence supports the beneficial effects of berries on glucoregulation, possibly related to flavonoid content, fiber content, or both. The purpose of this study was to assess the potential of mixed berries to improve insulin sensitivity and to identify the potential role of flavonoids and fiber. In a randomized cross-over trial with four treatment periods, overweight/obese men and women were fed a controlled 45% fat diet for one week prior to a meal-based glucose tolerance test. The same base diet was provided during each feeding period with the addition of one of four treatments: whole mixed berries, sugar matched mixed berry juice, sugar matched gelatin, and sugar/fiber matched gelatin. Subjects then completed a meal-based oral glucose tolerance test. Serum glucose, insulin and non-esterified fatty acids were not different between individual treatments. However, in a secondary analysis, the combined berry preparations resulted in a lower serum insulin area under the curve (difference of 0.15 ± 0.066 ln pmol min/mL, mean ± SE,

Indexed as

Insulin ResistanceOverweightAdultAgedAnthocyaninsCross-Over StudiesDietFemaleFood AnalysisFruitFruit and Vegetable JuicesGlucose Tolerance TestHumansMaleMiddle AgedPhenolsAnthocyaninsPhenolsberriesdiabetesinsulin sensitivityT2DM

Identifiers

PMID31775396
PMCPMC6950395
OpenAlexW2991596649

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.