Evidence map›Paper›PMID 31775314›Full record

ArticleNanomaterials (Basel, Switzerland)2019

Revealing the Importance of Aging, Environment, Size and Stabilization Mechanisms on the Stability of Metal Nanoparticles: A Case Study for Silver Nanoparticles in a Minimally Defined and Complex Undefined Bacterial Growth Medium.

Ilse De Leersnyder, Leen De Gelder, Isabel Van Driessche, Pieter Vermeir

Abstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  9. Enhancing Dental Alginate withGels (Basel, Switzerland) · 2024
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  16. Synthesis ofNanomaterials (Basel, Switzerland) · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ilse De LeersnyderLaboratory of Chemical Analysis (LCA), Department of Green Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, 9000 Ghent, Belgium.ORCID 0000-0002-5070-2487
Leen De GelderDepartment of Biotechnology, Laboratory for Environmental Biotechnology, Faculty of Bioscience Engineering, Ghent University, 9000 Ghent, Belgium.
Isabel Van DriesscheDepartment of Chemistry, Sol-Gel Center for Research on Inorganic Powders and Thin Film Synthesis (SCRiPTS), Faculty of Sciences, 9000 Ghent, Belgium.
Pieter VermeirLaboratory of Chemical Analysis (LCA), Department of Green Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, 9000 Ghent, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although the production and stabilization of metal nanoparticles (MNPs) is well understood, the behavior of these MNPs (possible aggregation or disaggregation) when they are intentionally or unintentionally exposed to different environments is a factor that continues to be underrated or overlooked. A case study is performed to analyze the stability of silver nanoparticles (AgNPs)-one of the most frequently used MNPs with excellent antibacterial properties-within two bacterial growth media: a minimally defined medium (IDL) and an undefined complex medium (LB). Moreover, the effect of aging, size and stabilization mechanisms is considered. Results clearly indicate a strong aggregation when AgNPs are dispersed in IDL. Regarding LB, the 100 nm electrosterically stabilized AgNPs remain stable while all others aggregate. Moreover, a serious aging effect is observed for the 10 nm electrostatically stabilized AgNPs when added to LB: after aggregation a restabilization effect occurs over time. Generally, this study demonstrates that the aging, medium composition (environment), size and stabilization mechanism-rarely acknowledged as important factors in nanotoxicity studies-have a profound impact on the AgNPs stabilization and should gain more attention in scientific research.

Indexed as

aggregationagingAgNPssizestabilization mechanismtest medium

Identifiers

PMID31775314
PMCPMC6955861

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.