Evidence map›Paper›PMID 31775131›Full record

ArticlePhysics in medicine and biology2020

Fast-switching dual energy cone beam computed tomography using the on-board imager of a commercial linear accelerator.

Roberto Cassetta, Mathias Lehmann, Maksat Haytmyradov, Rakesh Patel, Adam Wang, Luca Cortesi, Daniel Morf, Dieter Seghers, Murat Surucu, Hassan Mostafavi and 1 more

Open access · greenAbstract read
In one paragraph

Article in Physics in medicine and biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
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  5. Multi-Material Decomposition Using Spectral Diffusion Posterior Sampling.IEEE transactions on bio-medical engineering · 2025
    Article
  6. Article
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  8. CT Material Decomposition using Spectral Diffusion Posterior Sampling.Conference proceedings. International Conference on Image Formation in X-Ray Computed Tomography · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Roberto CassettaDivision of Medical Physics, Department of Radiation Oncology, Loyola University Medical Center, Maywood, IL, United States of America.ORCID 0000-0002-3073-4131
Mathias LehmannVarian Medical Systems, Baden-Dättwil, Switzerland.
Maksat HaytmyradovDivision of Medical Physics, Department of Radiation Oncology, Loyola University Medical Center, Maywood, IL, United States of America.
Rakesh PatelDivision of Medical Physics, Department of Radiation Oncology, Loyola University Medical Center, Maywood, IL, United States of America.
Adam WangStanford University, Stanford, CA, United States of America.
Luca CortesiVarian Medical Systems, Baden-Dättwil, Switzerland.
Daniel MorfVarian Medical Systems, Baden-Dättwil, Switzerland.
Dieter SeghersVarian Medical Systems, Baden-Dättwil, Switzerland.
Murat SurucuDivision of Medical Physics, Department of Radiation Oncology, Loyola University Medical Center, Maywood, IL, United States of America.
Hassan MostafaviVarian Medical Systems, Palo Alto, CA, United States of America.
John C RoeskeDivision of Medical Physics, Department of Radiation Oncology, Loyola University Medical Center, Maywood, IL, United States of America.
Loyola University Medical Center · USVarian Medical Systems (Switzerland) · CHStanford University · USVarian Medical Systems (United States) · US

Funding

Markerless Motion Tracking of Lung Tumors Using Dual Energy ImagingR01CA207483 · NCI · LOYOLA UNIVERSITY CHICAGO · PI LEHMANN, MATHIAS, ROESKE, JOHN · 2017 to 2025
$2.2M
NCI NIH HHS R01 CA207483
6 · The paper itself

Abstract

To evaluate fast-kV switching (FS) dual energy (DE) cone beam computed tomography (CBCT) using the on-board imager (OBI) of a commercial linear accelerator to produce virtual monoenergetic (VM) and relative electron density (RED) images. Using an polynomial attenuation mapping model, CBCT phantom projections obtained at 80 and 140 kVp with FS imaging, were decomposed into equivalent thicknesses of aluminum (Al) and polymethyl methacrylate (PMMA). All projections were obtained with the titanium foil and bowtie filter in place. Basis material projections were then recombined to create VM images by using the linear attenuation coefficients at the specified energy for each material. Similarly, RED images were produced by replacing the linear attenuation values of Al and PMMA by their respective RED values in the projection space. VM and RED images were reconstructed using Feldkamp-Davis-Kress (FDK) and an iterative algorithm (iCBCT, Varian Medical Systems). Hounsfield units (HU), contrast-to-noise ratio (CNR) and RED values were compared against known values. The results after VM-CBCT production showed good material decomposition and consistent HU

Indexed as

AlgorithmsPhantoms, ImagingCone-Beam Computed TomographyHumansImage Processing, Computer-AssistedParticle Accelerators

Identifiers

PMID31775131
PMCPMC7043019
OpenAlexW2991279275

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.